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ABZ/PPENK微球的制备及其表征

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Indexed by:期刊论文

Date of Publication:2019-05-30

Journal:功能材料

Included Journals:PKU

Volume:50

Issue:5

Page Number:5152-5154,5159

ISSN No.:1001-9731

Key Words:阿苯达唑;聚芳醚腈酮;微球;制备

Abstract:研究了乳化溶剂挥发法制备ABZ-PPENK微球的方法.利用扫描电镜、透射电镜、红外光谱表征了ABZ-PPENK微球的形态及结构,利用光学显微镜计算了微球的粒径分布,并筛分出不同粒径段的ABZ-PPENK微球,计算了微球的载药量与包封率.制备的ABZ-PPENK微球,表面光滑、球形圆整,制得的微球平均粒径为9.9μm,微球粒径接近正态分布,ABZ药物完全被包裹在PPENK微球之中,且载药量与包封率均较高.

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