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论文类型：期刊论文

发表时间：2013-01-01

发表刊物：JOURNAL OF ANIMAL AND VETERINARY ADVANCES

收录刊物：SCIE、Scopus

卷号：12

期号：5

页面范围：584-588

ISSN号：1680-5593

关键字：Anti-fatigue activity; crude sapomns' from Panax quinquefolium; forced swimming test; mice; liver glycogen

摘要：The present study was carried out to investigate anti-fatigue activity of Crude saponins from Panax quinquefolium (CPQS) in mice. The animals were randomly divided into four groups: control (distilled water); 50 mg kg(-1) CPQS; 100 mg kg(-1) CPQS and 200 mg kg CPQS. Distilled water or CPQS were orally administered for consecutive 28 days. The 28 days later, forced swimming test was performed and then fatigue-related biochemical parameters including blood lactic acid, serum urea nitrogen, liver glycogen and muscle glycogen were detected. The results showed that CPQS could prolong the swimming to exhaustion time of mice as well as increasing the liver and muscle glycogen contents but decrease the blood lactic acid and serum urea nitrogen levels. Therefore, the present study demonstrated that CPQS possessed anti-fatigue activity.