修志龙

个人信息Personal Information

教授

博士生导师

硕士生导师

性别:男

毕业院校:大连理工大学

学位:博士

所在单位:生物工程学院

学科:生物化工. 生物工程与技术

联系方式:zhlxiu@dlut.edu.cn

电子邮箱:zhlxiu@dlut.edu.cn

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微生物连续发酵建模及胞内动力学参数辨识

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论文类型:期刊论文

发表时间:2022-06-30

发表刊物:大连理工大学学报

期号:3

页面范围:458-463

ISSN号:1000-8608

摘要:A dynamical system concerning intracellular substances and transport patterns was proposed to describe glycerol bioconversion to 1, 3-propanediol in continuous fermentation process. Some properties of the system were subsequently discussed. Taking the error between the computational values and experimental data as the cost function, a parameter identification model to identify the intracellular kinetic parameters was established. The existence of the optimal parameters in the parameter identification model was also proved. Finally, an improved particle swarm optimization was constructed to solve the above parameter identification model. Numerical results show that the mean relative error is cut down by 20.635%, and the proposed algorithm has higher global convergence compared with other optimization algorithms.

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