Title of Paper:A Ligand-Free Copper-Catalyzed Decarboxylative Trifluoromethylation of Aryliodides with Sodium Trifluoroacetate Using Ag2O as a Promoter

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Date of Publication:2011-07-01

Journal:SYNLETT

Included Journals:SCIE

Issue:12

Page Number:1713-1716

ISSN No.:0936-5214

Key Words:copper-catalyzed; trifluoromethylation; decarboxylative; silver oxide; cross-coupling

Abstract:A practical and ligand-free Cu-catalyzed decarboxylative trifluoromethylation of aryl iodides with sodium trifluoroacetate using Ag2O as a promoter was reported. A variety of trifluoromethyl-substituted aromatics are synthesized in moderate to excellent yields and with wide functional-group tolerance under relatively mild reaction conditions.