个人信息Personal Information
副教授
硕士生导师
性别:女
毕业院校:辽宁师范大学
学位:硕士
所在单位:公共基础学院
电子邮箱:lyydut@dlut.edu.cn
Leveraging prior knowledge for protein-protein interaction extraction with memory network
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论文类型:期刊论文
发表时间:2018-07-13
发表刊物:DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
收录刊物:PubMed、SCIE、SSCI
卷号:2018
ISSN号:1758-0463
摘要:Automatically extracting protein-protein interactions (PPIs) from biomedical literature provides additional support for precision medicine efforts. This paper proposes a novel memory network-based model (MNM) for PPI extraction, which leverages prior knowledge about protein-protein pairs with memory networks. The proposed MNM captures important context clues related to knowledge representations learned from knowledge bases. Both entity embeddings and relation embeddings of prior knowledge are effective in improving the PPI extraction model, leading to a new state-of-the-art performance on the BioCreative VI PPI dataset. The paper also shows that multiple computational layers over an external memory are superior to long short-termmemory networks with the local memories.