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New Application of N-Halosuccinimide/PPh3 for the Halogenation of Propargyl Alcohols to Haloallenes

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Indexed by:期刊论文

Date of Publication:2009-01-01

Journal:SYNTHETIC COMMUNICATIONS

Included Journals:SCIE

Volume:39

Issue:21

Page Number:3940-3949

ISSN No.:0039-7911

Key Words:Haloallene; N-halosuccinimide; preparation; propargyl alcohol; triphenylphisphine

Abstract:An efficient and convenient new method has been developed for the preparation of haloallenes from propargyl alcohols by a reagent combination of N-halosuccinimide and triphenylphosphine. Chloroallenes 2 and bromoallenes 3 were obtained exclusively in moderate to good yields with regioselectivity.

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