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论文类型：期刊论文

第一作者：Shan, Bin

通讯作者：Zhang, SF (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China.

合写作者：Deng, Yong,Tang, Bingtao,Lu, Rongwen,Zhang, Shufen

发表时间：2016-04-05

发表刊物：CHEMISTRY LETTERS

收录刊物：SCIE

卷号：45

期号：4

页面范围：472-474

ISSN号：0366-7022

关键字：pH indicator; Naked eye; Thiazole-containing dye

摘要：A new pH indicator having high sensitivity and significant color change visible to the naked eye from red to blue in a narrow pH range (3.2-4.0) with high molar absorption coefficient was designed and synthesized from 2-amino-5-nitrothiazole and H-acid. The possible mechanism of the indicator was proposed by H-1 NMR and C-13 NMR titration experiments. This pH indicator was successfully applied in visualization of simulated gastric fluid acid pH changes in the simulated curing process of gastric ulcer.