徐征
开通时间:..
最后更新时间:..
点击次数:
论文类型:期刊论文
发表时间:2012-03-01
发表刊物:MICROFLUIDICS AND NANOFLUIDICS
收录刊物:SCIE、EI
卷号:12
期号:5
页面范围:829-834
ISSN号:1613-4982
关键字:Deposited microbead plug (DMBP); Whole-blood immunoassay; Capillary force; Microfluidics
摘要:We present a deposited microbead plug (DMBP)-based microfluidic chip capable of performing plasma extraction and on-chip immunoassay. The DMBP used as a porous blood filter provides pure blood plasma without the contamination of blood cells or beads. Capillary-driven flow eliminates the requirement of external pumps. The human IgG and goat anti-human IgG sample-to-answer assay was performed in this chip within 600 s using only a 10 mu l whole-blood sample. This easy-to-use, rapid, inexpensive, and disposable DMBP-based chip holds a great promise for point-of-care application.