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论文类型：期刊论文

发表时间：2012-08-01

发表刊物：ANALYTICAL METHODS

收录刊物：SCIE、EI、Scopus

卷号：4

期号：8

页面范围：2334-2340

ISSN号：1759-9660

摘要：A novel macro-micro modeling method has been presented for designing three-dimensional microfluidic devices in system-level. The macro model was used to solve mass transfer in simple modules of a microfluidic device, such as straight channels. The micro model was used to solve mass transfer in complicated modules of a microfluidic device, such as mixing channels. Then, the mass transfer in a microfluidic device was solved in system-level. The macro-micro modeling method was applied to a micromixer, and the concentration distribution in the micromixer can be evaluated. Compared with numerical simulation, the maximum relative deviation between macro-micro calculation and numerical simulation, results are 1.28% and the computational efficiency of macro-micro model was improved significantly with the numbers of straight channels increasing. The macromicro modeling method is proven to be an effective way for rapid design of microfluidic devices in system-level.