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论文类型：期刊论文

第一作者：Liu Sisi

通讯作者：Zhao, HX (reprint author), Dalian Univ Technol, Sch Environm Sci & Technol, Key Lab Ind Ecol & Environm Engn, Minist Educ, Linggong Rd 2, Dalian 116024, Peoples R China.; Qu, BC (reprint author), Dalian Inst Food Inspect, Dalian 116630, Peoples R China.

合写作者：Dong Guangbin,Zhao Hongxia,Chen Mo,Quan Wenna,Qu Baocheng

发表时间：2018-01-05

发表刊物：Environmental science and pollution research international

收录刊物：SCIE

卷号：25

期号：8

页面范围：8035-8043

ISSN号：1614-7499

关键字：Cultured fish,Fluoroquinolones,Risk assessment,Tetracyclines

摘要：Occurrence and levels of 11 fluoroquinolones (FQs) and four tetracyclines (TC) in 14 cultured fish species from a coastal city in the northern China were investigated. Five FQs (ofloxacin, enoxacin, ciprofloxacin, enrofloxacin, and sarafloxacin) and oxytetracycline were detected. Lower detection frequencies of antibiotics were observed in the marine fish. The concentrations of SigmaFQs ranged from not detectable (nd) to 130ng/g wet weight (ww) (median, 7.2ng/g ww), and the concentration range of SigmaTCs was nd to 200ng/g ww (median, nd ng/g ww). The Chinese snakehead contained the highest concentrations of SigmaFQs (130ng/g ww) and the small yellow croaker accumulated the highest concentrations of SigmaTCs (200ng/g ww), respectively. Although the calculated estimated daily intakes (EDI) suggested that the consumption of these cultured fish from this region was not associated with significant human health risks, this study provides useful information that will be helpful in the appropriate antibiotic use in aquaculture. To our knowledge, this can be the first report on the occurrence and levels of antibiotics in cage-cultured marine fish from the Bohai Rim region, China.