葛宏伟

个人信息Personal Information

教授

博士生导师

硕士生导师

主要任职:计算机科学与技术学院党委书记

性别:男

毕业院校:吉林大学

学位:博士

所在单位:计算机科学与技术学院

学科:计算机应用技术

办公地点:创新园大厦A832

联系方式:hwge@dlut.edu.cn

电子邮箱:gehw@dlut.edu.cn

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An automatic motif recognition algorithm in DNA sequences based on particle swarm optimization and random projection

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论文类型:会议论文

发表时间:2017-01-01

收录刊物:CPCI-S

卷号:2017-January

页面范围:2241-2243

关键字:motif recognition; random projection; particle swarm optimization

摘要:Motif recognition plays a significant role for understanding the biological meanings of sequences. In this paper, a particle swarm optimization and random projection based algorithm (PSORPS) is proposed for recognizing DNA motifs. First, noise subsequences are filtered by a random projection strategy for constructing objective space. Then the PSO is used to automatically search the motifs of DNA sequences in the constructed l-mer objective space. Finally, the operators of independent drift and associated drift are conducted on the optimization results to alleviate base deviation. The experiments are carried out on real-world biological datasets, and the results validate the effectiveness of the proposed algorithm.