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杜健军
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教授   博士生导师   硕士生导师

性别: 男

毕业院校: 大连理工大学

学位: 博士

所在单位: 化工学院

学科: 精细化工

办公地点: 大连理工大学西部校区E-226

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A BODIPY-based Fluorescent Probe for Thiophenol

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论文类型: 期刊论文

发表时间: 2018-02-01

发表刊物: CHINESE JOURNAL OF CHEMISTRY

收录刊物: SCIE、Scopus

卷号: 36

期号: 2

页面范围: 119-123

ISSN号: 1001-604X

关键字: thiophenol; BODIPY; fluorescent probe; cell imaging

摘要: Thiophenol has been listed as one of the main sources of pollution. Sensitive probes for thiophenol are very significant. Herein, a BODIPY-based fluorescent probe, named BDP, for poisonous thiophenol detection has been reported. BDP shows rapid response (15 s) and clear fluorescence enhancement (30 folds) to thiophenol in solution. The intensity of fluorescence and concentration of thiophenol have a good linear relationship. The detection limit is as low as 13.6 nmol L-1. BDP is stable towards pH and light radiation. Cell experiments demonstrate that BDP has good cell membrane penetrability, low cell toxicity and excellent imaging properties in living cells. Therefore, BDP has significant value on the detection of thiophenol in solution and in living cell.

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