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A cerium-based metal-organic tetrahedron for fluorescent recognition of 5-HIAA and its application in urine test

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Indexed by:期刊论文

Date of Publication:2016-11-01

Journal:INORGANIC CHEMISTRY COMMUNICATIONS

Included Journals:SCIE、Scopus

Volume:73

Page Number:129-133

ISSN No.:1387-7003

Key Words:Urine test; Tumor marker; Fluorescent sensor

Abstract:A cerium-based metal-organic tetrahedron including triphenylamine was applied to recognize the 5-hydroxyindole-3-acetic acid (5-HIAA), a kind of tumor marker and playing crucial roles in the process of the disease diagnosis and clinical treatment. The tetrahedron could encapsulate 5-HIAA through weak interaction and space stereoselectivity, and it displayed good fluorescence enhancement towards 5-HIAA over other relevant species in urine. The tetrahedral sensor is capable of detecting 5-HIAA with good selectivity and high sensitivity in real urine. (C) 2016 Elsevier B.V. All rights reserved.

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