个人信息Personal Information
副教授
硕士生导师
性别:女
毕业院校:兰州大学
学位:博士
所在单位:化工海洋与生命学院
联系方式:wang_li@dlut.edu.cn
电子邮箱:wang_li@dlut.edu.cn
个人简介Personal Profile
王黎,大连理工大学生命科学与药学学院,副教授,硕士生导师。2012年获兰州大学细胞生物学博士学位;美国Mayo Clinic 访问学者。目前已发表多篇研究论文,包括学科知名期刊 ACS Omega, Journal of Hematology & Oncology,Colloids and Surfaces B: Biointerfaces,International Journal of Pharmaceutics,Biomaterials,Food and Chemical Toxicology 等。
主要研究方向: 生物催化转化。
(1)工业微生物菌株的代谢工程改造,发酵过程优化及工程放大技术开发。
(2)微生物与酶催化转化研究,生物医药等高附加值生物基化学品的制备。
代表性论文:
1. Du WJ, Huang, J, Cui BC, Guo Y, Wang L*, Liang CH*., Efficient biodegradation of nitriles by a novel nitrile hydratase derived from Rhodococcus erythropolis CCM2595. Biotechnol Biotec Eq 2021, 35 (1), 1127-1135
2. Wang L, Liu SX, Du WJ, Dou TY, and Liang CH. High Regioselectivity Production of 5-Cyanovaleramide from Adiponitrile by a Novel Nitrile Hydratase Derived from Rhodococcus erythropolis CCM2595. ACS Omega 2020, 5(29):18397-18402
3. M Li, J Jia, S Li, B Cui, J Huang, Z Guo, K Ma, L Wang*, C Cui*, Exosomes derived from tendon stem cells promote cell proliferation and migration through the TGF beta signal pathway, Biochem Biophys Res Commun, 536 (2021) 88-94.
4. Guo Z*, Liu Y, Zhou H, Zheng K, Wang D, Jia M, Xu P, Ma K, Cui C, Wang L*: CD47-targeted bismuth selenide nanoparticles actualize improved photothermal therapy by increasing macrophage phagocytosis of cancer cells. Colloids Surf B Biointerfaces 2019, 184:110546.
5. Wang L, Yu D, Dai R, Fu D, Li W, Guo Z, Cui C, Xu J, Shen S, Ma K: PEGylated doxorubicin cloaked nano-graphene oxide for dual-responsive photochemical therapy. Int J Pharm 2019, 557:66-73.
6. Wang L, Cheng J, Lin F, Liu S, Pan H, Li M, Li S, Li N, Li W: Ortho-Topolin Riboside Induced Differentiation through Inhibition of STAT3 Signaling in Acute Myeloid Leukemia HL-60 Cells. Turk J Haematol 2019, 36(3):162-168.
7. Wang L, Yu DL, Zhang HW, He LY, Wu L, Ortho-topolin riboside induces apoptosis in Acute myeloid leukemia HL-60 cells, Molecular & Cellular Toxicology, 2016, 12(2):159-166.