马昆

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Associate Professor   Supervisor of Master's Candidates  

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科研项目:

1.大连理工大学-辽宁省肿瘤医院医工交叉联合基金,DUT21YG117, 多功能Janus纳米粒联合双氢青蒿素用于耐药性DLBCL的靶向治疗,2021/01-2022/12

2. 辽宁省自然科学基金面上项目,20170540155,多重靶向转座子CRISPR/Cas9基因载体的构建与应用,2017/05-2019/04

3. 教育部留学归国人员科研启动基金项目,第49批,原生细胞模型protocell作为基因载体的研究,2015/03-2017/03
4. 国家自然科学基金面上项目,30973647,基于介孔二氧化硅的门控靶向给药系统的构建与性能评价,2010/01-2012/12
5. 浙江省自然科学基金面上项目,Y2090229,新型双分子靶向基因传递系统的研究,2010/01-2011/12
6. 国家自然科学基金面上项目,30873175,“连环”靶向基因载体的研究与应用,2009/01-2009/12

已发表的论文:

[1] Guang Zhu, Hao Chi, Meichen Liu, Yalin Yin, He Diao, Zicheng Liu, Shibo Sun, Zhaoming Guo, Weiping Xu, Jianqiang Xu, Changhao Cui*, Xiao-Jin Xing*, Kun Ma*. Multifunctional “ball-rod” Janus nanoparticles boosting Fenton reaction for ferroptosis therapy of non-small cell lung cancer. Journal of Colloid and Interface Science. 2022, 621: 12-23. (SCI, IF=9.965)

[2] Hao Chi, Guang Zhu, Yalin Yin, He Diao, Zicheng Liu, Shibo Sun, Zhaoming Guo, Weiping Xu, Jianqiang Xu, Changhao Cui, Xiao-Jin Xing, Kun Ma*, Dual-Responsive multifunctional "core-shell" magnetic nanoparticles promoting Fenton reaction for tumor ferroptosis therapy, International Journal of Pharmaceutics, 2022,  622, 121898. (SCI, IF: 6.51)

[3] Kun Ma, Wenzhe Li, Guang Zhu, Shibo Sun, Hao Chi, Yalin Yin, He Diao, Xiao-Jin Xing, Zhaoming Guo, Li Wang, Weiping Xu, Changhao Cui, Jianqiang Xu*. Functionalized PDA/DEX-PEI@HA nanoparticles combined with sleeping-beauty transposons for multistage targeted delivery of CRISPR/Cas9 gene. Biomedicine & Pharmacotherapy. 2021, 142, 112061. (SCI, IF=7.419)

[4] Kun Ma, Wenzhe Li, Guang Zhu, Hao Chi, Yalin Yin, Yan Zong, Zhaoming Guo, Li Wang, Weiping Xu, Changhao Cui, Jianqiang Xu*. PEGylated DOX-coated Nano Graphene Oxide as pH-Responsive Multifunctional Nanocarrier for Targeted Drug Delivery. Journal of Drug Targeting. 2021, 29(8): 884-891. (SCI, IF=5.016)

[5] Yajun Liu, Rui Dai, Qiuyu Wei, Wenzhe Li, Guang Zhu, Hao Chi, Zhaoming Guo, Li Wang, Changhao Cui, Jianqiang Xu, Kun Ma*. Dual-Functionalized Janus Mesoporous Silica Nanoparticles with Active Targeting and Charge Reversal for Synergistic Tumor-Targeting Therapy. ACS Applied Materials & Interfaces. 2019, 11, 44582-44592. (SCI, IF=10.383)

[6] Li Wang, Dongli Yu, Rui Dai, Duo Fu, Wenzhe Li, Zhaoming Guo, Changhao Cui, Jianqiang Xu, Song Shen, Kun Ma*. PEGylated doxorubicin cloaked nano-graphene oxide for dual-responsive photochemical therapy. International Journal of Pharmaceutics. 2019, 25(557): 66-73. (SCI, IF=6.51)

[7] Kun Ma*, Duo Fu, Yajun Liu, Rui Dai, Dongli Yu, Zhaoming Guo, Changhao Cui, Li Wang, Jinaqiang Xu, Chuanbin Mao*. Cancer cell targeting, controlled drug release and intracellular fate of biomimetic membrane-encapsulated drug-loaded nano-graphene oxide nanohybrids. Journal of Materials Chemistry B. 2018, 6(31): 5080-5090. (SCI, IF=7.571)

[8] Kun Ma*, Duo Fu, Dongli Yu, Changhao Cui, Li Wang, Zhaoming Guo, Chuanbin Mao*. Targeted delivery of in situ PCR-amplified Sleeping Beauty transposon genes to cancer cells with lipid-based nanoparticle-like protocells. Biomaterials. 2017, 121:55-63. (SCI, IF=15.304)

[9] Kun Ma, Dong-Dong Wang, Yiyang Lin, Jianglin Wang, Valery Petrenko, Chuanbin Mao*. Synergetic targeted delivery of sleeping-beauty transposon system to mesenchymal stem cells using LPD nanoparticles modified with phage-displayed targeting peptide. Advanced Functional Materials, 2013, 23 (9): 1172-1181. (SCI, IF=19.924)

Educational ExperienceMore>>

2011.9 2013.3

  • 浙江大学
  • 药剂学
  • Doctoral Degree

2002.9 2005.7

  • 新疆医科大学
  • 药剂学
  • Master's Degree

1993.9 1997.7

  • 新疆医科大学
  • 药学
  • Bachelor's Degree

Work Experience

2014.9 Now
  • 大连理工大学
  • 副教授
2011.3 2014.2
  • 美国俄克拉玛大学化学系
  • 博士后

Social Affiliations

Research Focus

  • Drug/Gene targeting delivery system; Drug Nanotechnology; New Drugs and New Dosage Forms