宋锋玲
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Prof. Dr. Fengling Song obtained his PhD degree from Dalian University of Technology in 2005. Then he did postdoc research at Wayne State University and University of Pittsburgh in USA from 2006-2009. Now he is a professor at State Key Laboratory of Fine Chemicals of Dalian University of Technology.


Research Interests:

l   Pure Organic Materials with Thermally Activated Delayed Fluorescence or Room-temperature Phosphorescence

l   Near-Infrared Fluorescent Compounds and Materials for Bioimaging

l   Fluorogenic Chemosensors for Hazard Chemicals.

l   Nanosensors Based on Silica Hybrid Material

 

Representive Publications:

1. Jiao, Long; Song, Fengling;* Cui, Jingnan; Peng, Xiaojun. A near infrared heptamethine aminocyanine dye with a long-living excited triplet state for photodynamic therapy. Chemical Communications, 2018, 54, 9198 – 9201.

2. Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014136, 95909597.

3. Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration.  J. Am. Chem. Soc2008130, 16460–16461.

4. Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism.  J. Am. Chem. Soc. 2007129, 12354–12355. (Featured in C&E News 2007, October 1 issue, pg. 30.)

5. Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005127, 4170-4171.

 

Publications:

1.        Chen, Wenlong; Song, Fengling.* Thermally activated delayed fluorescence molecules and their new applications aside from OLEDs. Chinese Chemical Letters, 2019, in press.

2.        Liu, Zhiwei; Shi, Wenbo; Hong, Gaobo; Chen,Wenlong; Song, Bo; Peng, Xiaojun; Xiong, Xiaoqing;* Song, Fengling.* A dual-targeted theranostic photosensitizer based on a TADF fluorescein derivative. Journal of Controlled Release 2019, 310, 1−10.

3.        Jiao, Long; Zhang, Xiaoye; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Three-in-one Functional Silica Nanocarrier with Singlet Oxygen Generating, Storage/release and Self-monitoring for Enhanced Fractional Photodynamic Therapy. ACS Applied Materials & Interfaces 2019, 11, 27250-27257.

4.        Liu, Zhiwei; Song, Fengling;* Shi, Wenbo; Gurzadyan, Gagik; Yin, Huiyi; Song, Bo; Liang, Ri; Peng, Xiaojun. Nitroreductase-activatable theranostic molecules with high PDT efficiency under mild hypoxia based on a TADF fluorescein derivative. ACS Applied Materials & Interfaces 2019, 11, 15426−15435.

5.        Chen, Wenlong; Song, Fengling;* Tang, Shanliang; Hong, Gaobo; Wu,Yingnan; Peng, Xiaojun. Red-to-blue photon up-conversion with high efficiency based on a TADF fluorescein derivative. Chemical Communications, 2019, 55, 4375 - 4378

6.        Tang, Shanliang; Song, Fengling;* Lu, Meiheng; Han, Keli; Peng, Xiaojun. A Visible-Light Photochromic Diarylethene: A Simple Strategy by Extending Conjugation with Electron Donating Groups. SCIENCE CHINA Chemistry 2019, 62, 451-459.

7.        Jiao, Long; Song, Fengling;* Cui, Jingnan; Peng, Xiaojun. A near infrared heptamethine aminocyanine dye with a long-living excited triplet state for photodynamic therapy. Chemical Communications, 2018, 54, 9198 – 9201.

8.        Liu, Zhiwei; Song, Fengling;* Song, Bo; Jiao, Long; An, Jing; Yuan, Jingli; Peng, Xiaojun. A FRET chemosensor for hypochlorite with large Stokes Shifts and long-lifetime emissions. Sensors & Actuators: B. Chemical 2018, 262958-965.

9.        An, Jing; Wu, Yingnan; Lu, Meiheng; Han, Keli; Song, Fengling;* Peng, Xiaojun. Long-Wavelength Chromophores with Thermally Activated Delayed Fluorescence Based on Fluorescein Derivatives. Journal of Photonics for Energy, 2018, 8(3), 032103.

10.     Song, Fengling;* Liang, Ri; Deng, Jundie; Liu, Zhiwei, Peng, Xiaojun. Fine-tailoring the linker of near-infrared fluorescence probes for nitroreductase imaging in hypoxic tumour cells. Chinese Chemical Letters, 2017, 28, 1997-2000.

11.     Jiao, Long; Song, Fengling;* Zhang, Biyou; Ning, Houfu; Cui, Jingnan;* Peng, Xiaojun. Improving brightness and photostability of NIR fluorescent silica nanoparticles through rational fine-tuning of the covalent encapsulation methods. Journal of Materials Chemistry B, 2017, 5, 5278 - 5283

12.     Wu, Yingnan; Song, Fengling;* Luo, Wenfang; Liu, Zhiwei; Song, Bo; Peng, Xiaojun. Enhanced Thermally Activated Delayed Fluorescence in New Fluorescein Derivatives By Introducing Aromatic Carbonyl Groups. ChemPhotoChem 2017, 1, 79-83.

13.     Wang, Xu; Song, Fengling;* Peng, Xiaojun. A versatile fluorescent probe for imaging viscosity and hypochlorite in living cells. Dyes & Pigments. 2016, 125, 89-94

14.     Xiong, Xiaoqing; Zheng, Laijiu;* Yan, Jun; Ye, Fang; Qian, Yongfang; Song, Fengling.*A turn-on and colorimetric metal-free long lifetime fluorescent probe and its application for time-resolved luminescent detection and bioimaging of cysteine. RSC Adv., 2015, 5, 53660-53664.

15.     Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 95909597

16.     Song, Fengling;* Ning, Houfu; She, Haiying; Wang, Jingyun; Peng, Xiaojun. A turn-on fluorescent probe for Au3+ based on rodamine derivative and its bioimaging application. Science China Chemistry. 2014, 57, 10431047

17.     Song, Fengling;* Xue,Yingying; Wang, Xu; Wang, Jingyun; Xiong, Xiaoqing; Peng, Xiaojun. Ratiometric fluorescent probe based on novel red-emission BODIPY for determination of bovine serum albumin. Chemical Research in Chinese Universities. 2014, 30, 738742.

18.     Chen, Bo; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun. A Highly Sensitive Fluorescent Chemosensor for Ruthenium: Oxidation Plays Triple Roles. Chem. A Eur. J., 2013, 19,10115-10118.

19.     She, Haiying; Song, Fengling;* Xu, Juan; Xiong, Xiaoqing; Chen,Gengwen; Fan, Jiangli; Sun, Shiguo; Peng, Xiaojun.* A New Tridentate Sulfur Receptor as A Highly Selective and Sensitive Fluorescent Sensor for Cu2+ ions. Chem. An Asian J., 2013, 8,2762-2767.

20.     Wang, Junyu; Song, Fengling;* Wang, Jingyun; Peng, Xiaojun.* A Near-infrared and Ratiometric Fluorescent Chemosensor for Palladium. Analyst, 2013, 138, 3667-3672.

21.     Chen,Gengwen; Song, Fengling;* Xiong, Xiaoqing; Peng, Xiaojun.* Fluorescent Nanosensors Based on Fluorescence Resonance Energy Transfer (FRET). Ind. Eng. Chem. Res., 2013, 52, 11228-112245..

22.     Xiong, Xiaoqing; Song, Fengling;* Chen, Gengwen; Sun, Wen; Wang, Jingyun; Gao, Pan; Zhang, Yukang; Qiao,Bo; Li, Wenfang; Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun.* Construction of Long-Wavelength Fluorescein Analogues and Their Application as Fluorescent Probes. Chem. A Eur. J., 2013,19, 6538-6545.

23.     Xiong, Xiaoqing; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun.* Red-Emissive Fluorescein Derivatives and Detection of Bovine Serum Albumin. Asian J. Org. Chem., 2013, 2, 145 – 149.

24.     Chen,Gengwen; Song, Fengling;* Wang, Jingyun; Yang, Zhigang; Sun,Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun.* FRET spectral unmixing: a ratiometric fluorescent nanoprobe for hypochlorite. Chem.Commun., 2012, 48 (24), 2949 – 2951.

25.     Chen,Gengwen; Song, Fengling;* Wang, Xu; Fan, Jiangli; Sun,Shiguo; Qiang, Xinxin; Dou, Bairui; Peng, Xiaojun.* Bright and Stable Cy3-Encapsulated Fluorescent Silica Nanoparticles with a Large Stokes Shift. Dyes & Pigments. 2012,93,1532-1537

26.     Koide, Kazunori;* Osman, Sami; Garner, Amanda L; Song, Fengling; Dixon, Tracy; Greenberger, Joel S; Epperly, Michael W. The Use of 3,5,40-Tri-O-acetylresveratrol as a Potential Prodrug for Resveratrol Protects Mice from γ-Irradiation-Induced Death. ACS Med. Chem. Lett. 2011, 2, 270–274

27.     Peng, Xiaojun;* Yang, Zhigang; Wang, Jingyun; Fan, Jiangli; He, Yanxia; Song, Fengling; Wang, Bingshuai; Sun, Shiguo; Qu, Junle; Qi, Jing; Yan, Meng. Fluorescence Ratiometry and Fluorescence Lifetime Imaging: Using a Single Molecular Sensor for Dual Mode Imaging of Cellular Viscosity. J. Am. Chem. Soc.. 2011, 133, 6626–6635

28.     Peng, Xiaojun;* Wu, Tong; Fan, Jiangli; Wang, Jingyun; Zhang, Si; Song, Fengling; Sun, Shiguo. An Effective Minor Groove Binder as a Red Fluorescent Marker for Live-Cell DNA Imaging and Quantification. Angew. Chem. Int. Ed. 2011, 50, 4180 4183

29.     Song, Fengling; Carder, Evan J.; Kohler, Clare C.; Koide, Kazunori.* Studies Toward an Ideal Fluorescence Method to Measure Palladium in Functionalized Organic Molecules: Effects of Sodium Borohydride, Temperature, Phosphine Ligand, and Phosphate Ions on Kinetics. Chem.-Eur. J., 2010, 16,13500-13508.

30.     Li, Honglin; Fan, Jiangli; Song, Fengling; Zhu, Hao; Du, Jianjun; Sun, Shiguo; Peng, Xiaojun.* Fluorescent Probes for Pd2+ Detection by AllylideneHydrazone Ligands with Excellent Selectivity and Large Fluorescence Enhancement. Chem.-Eur. J., 2010, 16,12349-12356.

31.     Song, Fengling; Wang, Li; Qiao, Xiaoqiang; Wang, Bingshuai; Sun, Shiguo; Fan, Jiangli; Zhang, Lihua; Peng, Xiaojun.* Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein Labeling. Org. Biomol. Chem., 2010, 8, 4249–4251

32.     Garner, Amanda L; Song, Fengling; Koide, Kazunori.* Enhancement of a Catalysis-Based Fluorometric Detection method for palladium through rational fine-tuning of the palladium species.  J. Am. Chem. Soc. 2009, 131, 5163-5171.

33.     Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration.  J. Am. Chem. Soc. 2008, 130, 16460–16461.

34.     Koide, Kazunori;* Song, Fengling; de Groh, Eric D.; Garner, Amanda L.; Mitchell, Valerie D.; Davidson, Lance A.; Hukriede, Neil A. Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. ChemBioChem 2008, 9, 214128.

35.     Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism.  J. Am. Chem. Soc. 2007, 129, 12354–12355. (Featured in C&E News 2007, October 1 issue, pg. 30.)

36.     Wang, Yanan; Guo, Xinwen;* Zhang, Chen; Song, Fengling; Wang, Xiangsheng; Liu, Hai-ou; Xu, Xiaochun; Song, Chunshan; Zhang, Weiping; Liu, Xiumei; Han, Xiuwen; Bao, Xinhe.   Influence of calcination temperature on the stability of fluorinated nanosized HZSM-5 in the methylation of biphenyl. Catal. Lett. 2006, 107, 209-214.

37.     Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171.

38.     Song, Fengling; Peng, Xiaojun;* Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli. Tuning the photoinduced electron transfer in near-infrared heptamethine cyanine dyes. Tetrahedron Lett. 2005, 46, 4817-4820.

39.     Lu, Erhu; Peng, Xiaojun;* Song, Fengling; Fan, Jiangli. A novel fluorescent sensor for triplex DNA. Bioorg. Med. Chem. Lett. 2005, 15(2), 255-257.

40.     Song, Fengling; Peng, Xiaojun;* Lu, Erhu; Zhang, Rong; Chen, Xiuying; Song, Bo. Syntheses, spectral properties and photostabilities of novel water-soluble near-infrared cyanine dyes. J. of Photochem. & Photobio. A: Chem. 2004, 168, 53–57.

41.     Wang, Liqiu; Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Cui, Jingnan; Gao, Xinqin; Lu, Rongwen. New near-infrared indocyanines and their spectral properties in SiO2 sol-gel. Dyes and Pigments. 2004, 61(2), 103-107.



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Personal Information

Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

Gender:Male

Alma Mater:Dalian University of Technology

Degree:Doctoral Degree

Status:On the job

School/Department:State Key Laboratory of Fine Chemicals

Discipline:Applied Chemistry Organic Chemistry Physical Chemistry (including Chemical Physics)

Business Address:E228 West Campus, 2 Linggong Rd.,Dalian, Liaoning, 116024, P. R. China

Contact Information:Email: songfl@dlut.edu.cn Tel: 86-411-84986307

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Address: No.2 Linggong Road, Ganjingzi District, Dalian City, Liaoning Province, P.R.C., 116024

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