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Improving the brightness and photostability of NIR fluorescent silica nanoparticles through rational fine-tuning of the covalent encapsulation methods
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Indexed by:Journal Papers

First Author:Jiao, Long

Correspondence Author:Song, FL; Cui, JN (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, 2 Linggong Rd, Dalian 116024, Peoples R China.

Co-authors:Song, Fengling,Zhang, Biyou,Ning, Houfu,Cui, Jingnan,Peng, Xiaojun

Date of Publication:2017-07-14

Journal:JOURNAL OF MATERIALS CHEMISTRY B

Included Journals:SCIE、EI、Scopus

Volume:5

Issue:26

Page Number:5278-5283

ISSN No.:2050-750X

Abstract:Near-infrared (NIR) fluorescence imaging technology calls for highly bright and photostable emissive materials for long-term and real-time bioimaging and medical diagnosis. Herein, we report that four aminocyanine dyes were covalently encapsulated inside silica nanoparticles by reverse microemulsion using different linkage methods. The fluorescence brightness and photostability of the obtained fluorescent silica nanoparticles (FSNPs) were found to have direct correlation with the used covalent encapsulation methods, especially the number of anchoring sites of the encapsulated dyes. The aminocyanine dye 4-Si contains three anchoring sites for embedding into the silica nanoparticles, and provides FSNP-4- the FSNP with the best brightness and photostability.

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Academic Titles:

Gender:Male

Alma Mater:Dalian University of Technology

Degree:Doctoral Degree

Status:On the job

School/Department:State Key Laboratory of Fine Chemicals

Discipline:Applied Chemistry Organic Chemistry Physical Chemistry (including Chemical Physics)

Business Address:E228 West Campus, 2 Linggong Rd.,Dalian, Liaoning, 116024, P. R. China

Contact Information:Email: songfl@dlut.edu.cn Tel: 86-411-84986307

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Address: No.2 Linggong Road, Ganjingzi District, Dalian City, Liaoning Province, P.R.C., 116024

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