Guangrui Yang

Professor   Supervisor of Doctorate Candidates   Supervisor of Master's Candidates

Main positions:生物工程学院副院长


Alma Mater:Peking University

Degree:Doctoral Degree

School/Department:School of Life Science and Biotechnology

Discipline:Chemical Biology. Physiology. Biological Engineering and Technology

Business Address:2 Linggong Road, Ganjingzi District, Dalian, Liaoning 116024, People's Republic of China

Contact Information:+8641184706806

Educational Experience

2002.8 -- 2007.7

Peking University       Pathophysiology       PhD

1994.8 -- 1999.6

The Second Military Medical University       Clinical Medicine       MD

Research Focus

1. The function of biological clock in diseases 2. The function of biological clock in development, aging, and behavior 3. Development of clock-targeted drugs

Work Experience

2017.3 -- Now


2014.11 -- 2017.3

美国宾夕法尼亚大学      研究助理教授

2011.11 -- 2014.10

美国宾夕法尼亚大学      助理研究员

2010.1 -- 2011.10

美国宾夕法尼亚大学      博士后

2007.6 -- 2010.1

美国犹他大学      博士后

1999.7 -- 2002.3

中国人民解放军总后勤部青藏兵站部      住院医师


The circadian rhythm is any biological process that displays an endogenous, entrainable oscillation of about 24 hours. These rhythms are driven by circadian clocks and have been widely observed in animals, plants, fungi, and some bacteria. Before I started research in Chronobiology, I investigated the role of PPARgamma, a key metabolic nuclear receptor, in blood pressure regulation. When I found this gene was involved in circadian rhythm, I was deeply captivated. The clock in organism is like sine curve in trigonometry, wave in physics and melody in music. What a beautiful picture the cycle of life is! My current aim is to investigate the role of circadian clock in aging and behavior, as well as multiple diseases including cardiovascular diseases and metabolic diseases. My long-term goal is to find a way to cure jet lag and shift work induced diseases or disorders. PUBLICATIONS: