Fantao Kong   

Associate Professor
Supervisor of Master's Candidates

Academic Titles: Associate Professor

MORE>
Language:English

Personal Profile


Dr. Fantao Kong


Dr. Kong is a Professor (Associate) in Dalian University of Technology (DUT). His research interests including lipid biology and biotechnology using photosynthetic microalgae as model.


He obtained his Master’s degree majoring in Biochemistry and Molecular Biology from Harbin Institute of Technology (HIT) in China (2011), and got his Ph.D. degree majoring in Molecular Genetics in Kochi University of Technology (KUT) in Japan (2014). He completed Ph.D study about production of the hydrocarbon botryococcene from the model microalga Chlamydomonas reinhardtii through expressing squalene synthase-like genes (SSLs) of Botryococcus braunii, then he worked as a postdoctoral fellow in CEA Cadarache, CNRS in France (2014-2017), where he found Chlamydomonas carries out fatty acid b-oxidation in peroxisomes using a bona fide acyl-CoA oxidase (ACX2), and peroxisomal malate dehydrogenase 2 (MDH2) connects lipid catabolism to photosynthesis through redox coupling (Kong et al. 2017 Plant Journal; Kong et al. 2018 Plant Cell). After that, he worked in Pohang University of Science and Technology (POSTECH, South Korea) as a Researcher (2018-2019), there he focuses on how transcription factor (Yamaoka et al. 2019 Plant Cell), ABC transporter (Song et al. 2020 Molecules and Cells), and lipid hydrolysis enzyme modulate the lipid biosynthesis and degradation in microalgae. Sicence 2018, Dr. Kong works as a Professor (Associate) in DUT to study lipid metabolism and synthetic biology in microalgae.


Dr. Kong’ representative results about microalgae lipid metabolism were recently published in Plant Cell, New Phytologist, Plant Physiology, Plant Journal, Plant & Cell Physiology, Molecules and Cells, and Plant Molecular Biology etc. 


Emailkongfantao@dlut.edu.cn


Representative Publications in International Journals:


1.  Kong F*, Yamaoka Y, Ohama T, Lee Y, Li-Beisson Y. Molecular Genetic Tools and Emerging Synthetic Biology Strategies to Increase Cellular Oil Content in Chlamydomonas reinhardtii. (2019 June; 60(6): 1184–1196) Plant & Cell Physiology. (*Corresponding author). doi:org/10.1093/pcp/pcz022

2. Jang S, Kong F, Lee J, Choi B, Wang P, Gao P, Yamano T, Fukuzawa H, Kang B, Lee Y (2020). CrABCA2 Facilitates Triacylglycerol Accumulation in Chlamydomonas reinhardtii under Nitrogen Starvation. (†Co-first authors, 2020; 43(1): 48-57). Molecules and Cells. doi.org/10.14348/molcells.2019.0262

3. Yang M, Kong F, Xie X, Wu P, Chu Y, Cao X,Xue S (2020). Galactolipid DGDG and Betaine Lipid DGTS Direct De Novo Synthesized Linolenate into Triacylglycerol in Stress-induced Starchless Mutant of Chlamydomonas reinhardtii. (2020, Acceptted) Plant & Cell Physiology. https://doi.org/10.1093/pcp/pcaa012

4. Zhu C, Zhai X, Xi Y,  Wang J, Kong F, Zhao Y, Chi Z (2020). Efficient CO2 Capture from the Air for High Microalgal Biomass Production by a Bicarbonate Pool. (2020, 37, 320-327) Journal of CO2 Utilization.

5. Romero IT,  Kong F, Légeret B, Beisson F, Peltier G, Li-Beisson Y (2020).Chlamydomonas cell cycle mutant crcdc5 over-accumulates starch and oil. Biochimie. (2020 February, 169, 54-61) DOI: https://doi.org/10.1016/j.biochi.2019.09.017

6.  Liang Y, Kong F, Romero IT, Burlacot A, Cuiné S, Légeret B, Billon E, Brotman Y, Alseekh S, Fernie A, Beisson F, Peltier G, Li-Beisson Y (2019). Branched-Chain Amino Acid Catabolism Impacts Triacylglycerol Homeostasis in Chlamydomonas reinhardtii. (2019 Feb; Epub ahead of print) Plant Physiology. doi.org/10.1104/pp.18.01584

7.  Kong F, Burlacot A, Liang Y, Légeret B, Alseekh S, Brotman Y, Fernie A, Krieger-Liszkay A, Beisson F, Peltier G, Li-Beisson Y (2018). Interorganelle Communication: Peroxisomal MALATE DEHYDROGENASE2 Connects Lipid Catabolism to Photosynthesis through Redox Coupling in Chlamydomonas. (2018 August; (30):1824–1847) Plant Cell. doi: 10.1105/tpc.18.00361

8. Zhu C, Zhai X, Xi Y, Wang J, Kong F, Zhao Y, Chi Z (2019). Progress on the development of floating photobioreactor for microalgae cultivation and its application potential. (2019 Nov 21;35(12):190) World Journal of Microbiology and Biotechnology. doi.org/10.1007/s11274-019-2767-x

9. Yamaoka Y, Shin S, Choi B, Kim H, Jang S, Yamano T, Kajikawa M, Kong F, Légeret B, Li-Beisson Y, Fukuzawa H, Lee Y (2019). The bZIP1 Transcription Factor Regulates Lipid Remodeling and Contributes to ER Stress Management in Chlamydomonas reinhardtii. Plant Cell. (2019 May;31(5):1127-1140).doi.org/10.1105/tpc.18.00723

10.  Kong F, Romero IT, Warakanont J, Li-Beisson Y (2018).Lipid catabolism in microalgae. (2018 June; 218(4): 1340-1348) New Phytologist. doi: 10.1111/nph.15047

11.  Kong F*, Li-Beisson Y (2018). Identification of Insertion Site by RESDA-PCR in Chlamydomonas Mutants Generated by AphVIII Random Insertional Mutagenesis. (2018 February; (03)8:e2718) Bioprotocol (*Corresponding author). https://bio-protocol.org/e2718

12.  Kong F, Liang Y, Légeret B, Beyly-Adriano A, Blangy S, Haslam RP, Napier JA, Beisson F, Peltier G, Li-Beisson Y (2017). Chlamydomonas carries out fatty acid β-oxidation in ancestral peroxisomes using a bona fide acyl-CoA oxidase. (2017 April; 90(2):358-371) Plant Journal. doi: 10.1111/tpj.13498

13.  Goold HD #, Nguyen HM #, Kong F, Beyly-Adriano A, Légeret B, Billon E, Cuiné S, Beisson F, Peltier G, Li-Beisson Y (2016). Whole genome re-sequencing identifies a quantitative trait locus repressing carbon reserve accumulation during optimal growth in Chlamydomonas reinhardtii. (2016 May; 6:25209) Scientific Report. #Co-first author. doi: 10.1038/srep25209

14.  Kurniasih SD, Yamasaki T, Kong F, Okada S, Widyaningrum D and Ohama T (2016). UV-mediated Chlamydomonas mutants with enhanced nuclear transgene expression by disruption of DNA methylation-dependent and independent silencing systems. (2016 December; 92 (6): 629-641) Plant Molecular Biology. https://link.springer.com/article/10.1007%2Fs11103-016-0529-9

15.  Kong F, Yamasaki T, Kurniasih SD, Hou L, Li X, Ivanova N, Okada S, Ohama T (2015). Robust expression of heterologous genes by selection marker fusion system in improved Chlamydomonas strains. (2015 Sep; 120(3):239-245) Journal of Bioscience and Bioengineering. doi: 10.1016/j.jbiosc.2015.01.005

16. Kong F, Yamasaki T and Ohama T (2014). Expression levels of domestic cDNA cassettes integrated in the nuclear genomes of various Chlamydomonas reinhardtii strains. (2014 May;117(5):613-616) Journal of Bioscience and Bioengineering. doi: 10.1016/j.jbiosc.2013.10.025

17. Hou L, Wang P, Kong F, Park H, Kobiro K, Ohama T (2013). Mesoporous TiO2 nanoparticles: a new material for biolistic bombardment. (2013 January; 61(1):58-60) Phycological Research. doi: 10.1111/j.1440-1835.2012.00671.x 


WIPO Patent:
Ohama T, (*), Yamasaki T, Park H-S, Kong F, Hou L, ボツリオコッカスブラウニーの単細胞単離方法及び単細胞培養方法。2013.8.22, Japan, WO2013121509 A1


Honors and Awards:

2019   Gold Medal of iGEM, PI, BOSTON, USA

2018   Researcher fellowship, POSTECH, South Korea

2014   Postdoc fellowship, National Center for Scientific Research (CNRS), France

2013   Academic research award, KUT, Japan


Project Funding:

National Natural Science Foundation of China (NSFC, 31900221), PI

Fundamental Research Funds for the Central Universities [DUT18RC(3)041], PI


Member of the Editorial Board:

Journal of Plant Sciences, Editor

The Open Microalgae Biotechnology, Associate Editor 

Journal of Plant Sciences and Agriculture Technology, Editor 

Biotechnology for Biofuels, Frontier in Plant Science, Plant and Cell Physiology
and Applied Microbiology and Biotechnology et al, Reviewer

 


Education Background

  • 2011.10-2014.9  

    Kochi University of Technology (KUT)       Molecular Genetics       Doctoral Degree

  • 2009.9-2011.7  

    Harbin Institute of Technology (HIT)       Biochemistry and Molecular Biology       Master's Degree

  • 2005.9-2009.6  

    Harbin Normal University       Biology Science       Bachelor's Degree

  • 2001.9-2004.7  

    Gannan No.2 Senior High School       *

Work Experience

  • 2018.11-Now

    Dalian University of Technology (DUT)      School of Life Science and Technology      副教授      Professor (Associate)

  • 2018.7-2018.11

    Pohang University of Science and Technology (POSTECH)      Plant Cell Biology Lab      助理研究员      Researcher

  • 2014.11-2017.11

    CEA Cadarache, CNRS, France      BIAM      博士后      Postdoc

Address: No.2 Linggong Road, Ganjingzi District, Dalian City, Liaoning Province, P.R.C., 116024
Click:    MOBILE Version DALIAN UNIVERSITY OF TECHNOLOGY Login

The Founding Time:..

The Last Update Time: ..