宋锋玲

基本信息Personal Information

教授

博士生导师

硕士生导师

性别:男

毕业院校:大连理工大学

学位:博士

在职信息:在职

所在单位:精细化工国家重点实验室

学科:应用化学 有机化学 物理化学

办公地点:大连理工大学西部校区化工实验楼E228室

联系方式:Email: songfl@dlut.edu.cn Tel: 86-411-84986307

电子邮箱:

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个人简介Personal Profile

宋锋玲,大连理工大学精细化工国家重点实验室教授,博士生导师,首批国家自然科学基金优秀青年项目获得者,教育部新世纪优秀人才计划入选者,大连市杰出青年科技人才培育计划入选者。主要从事有机荧光染料的结构性能与应用研究,并开展荧光染料及功能化荧光纳米粒子在生物医学领域的成像研究。研究成果获2007年全国百篇优秀博士学位论文提名奖; 2012年教育部自然科学一等奖;2012年辽宁省自然科学一等奖;2016年辽宁省自然科学学术成果论文类一等奖。

学习工作经历:
1995年09月至1999年07月大连理工大学应用化学专业,学士学位
1999年09月至2005年10月大连理工大学应用化学专业,博士学位
2006年01月至2006年11月美国Wayne State University化学系, 有机化学博士后
2006年12月至2009年11月美国University of Pittsburgh化学系, 有机化学博士后
2012年07月至2012年11月美国Washington University in St Louis医学院, 访问学者
2009年12月至2012年12月大连理工大学精细化工国家重点实验室副教授。
2012年12月至今 大连理工大学精细化工国家重点实验室教授
2014年06月至今 大连理工大学精细化工国家重点实验室博士生导师

代表性论文:
1. Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 9590−9597. (SCI当前被引44次)
2. Chen,Gengwen; Song, Fengling;* Wang, Jingyun; Yang, Zhigang; Sun,Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun.* FRET spectral unmixing: a ratiometric fluorescent nanoprobe for hypochlorite. Chem.Commun., 2012, 48 (24), 2949 - 2951. (SCI当前被引75次)
3. Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration. J. Am. Chem. Soc. 2008, 130, 16460–16461. (SCI当前被引157次)
4. Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism. J. Am. Chem. Soc. 2007, 129, 12354–12355. (Featured in C&E News 2007, October 1 issue, pg. 30.) (SCI当前被引159次)
5. Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171. (SCI当前被引261次)

逐年论文列表:

1.       Tang, Shanliang; Song, Fengling;* Lu, Meiheng; Han, Keli; Peng, Xiaojun. A Visible-Light Photochromic Diarylethene: A Simple Strategy by Extending Conjugation with Electron Donating Groups. SCIENCE CHINA Chemistry 2018,   10.1007/s11426-018-9381-1.

2.       Jiao, Long; Song, Fengling;* Cui, Jingnan; Peng, Xiaojun. A near infrared heptamethine aminocyanine dye with a long-living excited triplet state for photodynamic therapy. Chemical Communications, 2018, 54, 9198 – 9201.

3.       Liu, Zhiwei; Song, Fengling;* Song, Bo; Jiao, Long; An, Jing; Yuan, Jingli; Peng, Xiaojun. A FRET chemosensor for hypochlorite with large Stokes Shifts and long-lifetime emissions. Sensors & Actuators: B. Chemical 2018, 262958-965.

4.       An, Jing; Wu, Yingnan; Lu, Meiheng; Han, Keli; Song, Fengling;* Peng, Xiaojun. Long-Wavelength Chromophores with Thermally Activated Delayed Fluorescence Based on Fluorescein Derivatives. Journal of Photonics for Energy, 2018, 8(3), 032103.

5.       Song, Fengling;* Liang, Ri; Deng, Jundie; Liu, Zhiwei, Peng, Xiaojun. Fine-tailoring the linker of near-infrared fluorescence probes for nitroreductase imaging in hypoxic tumour cells. Chinese Chemical Letters, 2017, 28, 1997-2000.

6.       Jiao, Long; Song, Fengling;* Zhang, Biyou; Ning, Houfu; Cui, Jingnan;* Peng, Xiaojun. Improving brightness and photostability of NIR fluorescent silica nanoparticles through rational fine-tuning of the covalent encapsulation methods. Journal of Materials Chemistry B, 2017, 5, 5278 - 5283

7.       Wu, Yingnan; Song, Fengling;* Luo, Wenfang; Liu, Zhiwei; Song, Bo; Peng, Xiaojun. Enhanced Thermally Activated Delayed Fluorescence in New Fluorescein Derivatives By Introducing Aromatic Carbonyl Groups. ChemPhotoChem 2017, 1, 79-83.

8.       Wang, Xu; Song, Fengling;* Peng, Xiaojun. A versatile fluorescent probe for imaging viscosity and hypochlorite in living cells. Dyes & Pigments. 2016, 125, 89-94

9.       Xiong, Xiaoqing; Zheng, Laijiu;* Yan, Jun; Ye, Fang; Qian, Yongfang; Song, Fengling;*A turn-on and colorimetric metal-free long lifetime fluorescent probe and its application for time-resolved luminescent detection and bioimaging of cysteine. RSC Adv., 2015, 5, 53660-53664.

10.    Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 95909597

11.    Song, Fengling;* Ning, Houfu; She, Haiying; Wang, Jingyun; Peng, Xiaojun. A turn-on fluorescent probe for Au3+ based on rodamine derivative and its bioimaging application. Science China Chemistry. 2014, 57, 10431047

12.    Song, Fengling;* Xue,Yingying; Wang, Xu; Wang, Jingyun; Xiong, Xiaoqing; Peng, Xiaojun. Ratiometric fluorescent probe based on novel red-emission BODIPY for determination of bovine serum albumin. Chemical Research in Chinese Universities. 2014, 30, 738742.

13.    Chen, Bo; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun. A Highly Sensitive Fluorescent Chemosensor for Ruthenium: Oxidation Plays Triple Roles. Chem. A Eur. J., 2013, 19,10115-10118.

14.    She, Haiying; Song, Fengling;* Xu, Juan; Xiong, Xiaoqing; Chen,Gengwen; Fan, Jiangli; Sun, Shiguo; Peng, Xiaojun. A New Tridentate Sulfur Receptor as A Highly Selective and Sensitive Fluorescent Sensor for Cu2+ ions. Chem. An Asian J., 2013, 8,2762-2767.

15.    Wang, Junyu; Song, Fengling;* Wang, Jingyun; Peng, Xiaojun. A Near-infrared and Ratiometric Fluorescent Chemosensor for Palladium. Analyst, 2013, 138, 3667-3672.

16.    Chen,Gengwen; Song, Fengling;* Xiong, Xiaoqing; Peng, Xiaojun. Fluorescent Nanosensors Based on Fluorescence Resonance Energy Transfer (FRET). Ind. Eng. Chem. Res., 2013, 52, 11228-112245..

17.    Xiong, Xiaoqing; Song, Fengling;* Chen, Gengwen; Sun, Wen; Wang, Jingyun; Gao, Pan; Zhang, Yukang; Qiao,Bo; Li, Wenfang; Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun. Construction of Long-Wavelength Fluorescein Analogues and Their Application as Fluorescent Probes. Chem. A Eur. J., 2013,19, 6538-6545.

18.    Xiong, Xiaoqing; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun. Red-Emissive Fluorescein Derivatives and Detection of Bovine Serum Albumin. Asian J. Org. Chem., 2013, 2, 145 – 149.

19.    Chen,Gengwen; Song, Fengling;* Wang, Jingyun; Yang, Zhigang; Sun,Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun. FRET spectral unmixing: a ratiometric fluorescent nanoprobe for hypochlorite. Chem.Commun., 2012, 48 (24), 2949 - 2951  

20.    Chen,Gengwen; Song, Fengling;* Wang, Xu; Fan, Jiangli; Sun,Shiguo; Qiang, Xinxin; Dou, Bairui; Peng, Xiaojun. Bright and Stable Cy3-Encapsulated Fluorescent Silica Nanoparticles with a Large Stokes Shift. Dyes & Pigments. 2012,93,1532-1537

21.    Koide, Kazunori; Osman, Sami; Garner, Amanda L; Song, Fengling; Dixon, Tracy; Greenberger, Joel S; Epperly, Michael W. The Use of 3,5,40-Tri-O-acetylresveratrol as a Potential Prodrug for Resveratrol Protects Mice from γ-Irradiation-Induced Death. ACS Med. Chem. Lett. 2011, 2, 270–274

22.    Peng, Xiaojun; Yang, Zhigang; Wang, Jingyun; Fan, Jiangli; He, Yanxia; Song, Fengling; Wang, Bingshuai; Sun, Shiguo; Qu, Junle; Qi, Jing; Yan, Meng. Fluorescence Ratiometry and Fluorescence Lifetime Imaging: Using a Single Molecular Sensor for Dual Mode Imaging of Cellular Viscosity. J. Am. Chem. Soc.. 2011, 133, 6626–6635

23.    Peng, Xiaojun; Wu, Tong; Fan, Jiangli; Wang, Jingyun; Zhang, Si; Song, Fengling; Sun, Shiguo. An Effective Minor Groove Binder as a Red Fluorescent Marker for Live-Cell DNA Imaging and Quantification. Angew. Chem. Int. Ed. 2011, 50, 4180 4183

24.    Song, Fengling; Carder, Evan J.; Kohler, Clare C.; Koide, Kazunori. Studies Toward an Ideal Fluorescence Method to Measure Palladium in Functionalized Organic Molecules: Effects of Sodium Borohydride, Temperature, Phosphine Ligand, and Phosphate Ions on Kinetics. Chem.-Eur. J., 2010, 16,13500-13508.

25.    Li, Honglin; Fan, Jiangli; Song, Fengling; Zhu, Hao; Du, Jianjun; Sun, Shiguo; Peng, Xiaojun. Fluorescent Probes for Pd2+ Detection by AllylideneHydrazone Ligands with Excellent Selectivity and Large Fluorescence Enhancement. Chem.-Eur. J., 2010, 16,12349-12356.

26.    Song, Fengling; Wang, Li; Qiao, Xiaoqiang; Wang, Bingshuai; Sun, Shiguo; Fan, Jiangli; Zhang, Lihua; Peng, Xiaojun. Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein Labeling. Org. Biomol. Chem., 2010, 8, 4249–4251

27.    Garner, Amanda L; Song, Fengling; Koide, Kazunori. Enhancement of a Catalysis-Based Fluorometric Detection method for palladium through rational fine-tuning of the palladium species.  J. Am. Chem. Soc. 2009, 131, 5163-5171.

28.    Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori. Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration.  J. Am. Chem. Soc. 2008, 130, 16460–16461.

29.    Koide, Kazunori; Song, Fengling; de Groh, Eric D.; Garner, Amanda L.; Mitchell, Valerie D.; Davidson, Lance A.; Hukriede, Neil A. Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. ChemBioChem 2008, 9, 214128.

30.    Song, Fengling; Garner, Amanda L; Koide, Kazunori. A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism.  J. Am. Chem. Soc. 2007, 129, 12354–12355. (Featured in C&E News 2007, October 1 issue, pg. 30.)

31.    Wang, Yanan; Guo, Xinwen; Zhang, Chen; Song, Fengling; Wang, Xiangsheng; Liu, Hai-ou; Xu, Xiaochun; Song, Chunshan; Zhang, Weiping; Liu, Xiumei; Han, Xiuwen; Bao, Xinhe.   Influence of calcination temperature on the stability of fluorinated nanosized HZSM-5 in the methylation of biphenyl. Catal. Lett. 2006, 107, 209-214.

32.    Peng, Xiaojun; Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171.

33.    Song, Fengling; Peng, Xiaojun; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli. Tuning the photoinduced electron transfer in near-infrared heptamethine cyanine dyes. Tetrahedron Lett. 2005, 46, 4817-4820.

34.    Lu, Erhu; Peng, Xiaojun; Song, Fengling; Fan, Jiangli. A novel fluorescent sensor for triplex DNA. Bioorg. Med. Chem. Lett. 2005, 15(2), 255-257.

35.    Song, Fengling; Peng, Xiaojun; Lu, Erhu; Zhang, Rong; Chen, Xiuying; Song, Bo. Syntheses, spectral properties and photostabilities of novel water-soluble near-infrared cyanine dyes. J. of Photochem. & Photobio. A: Chem. 2004, 168, 53–57.

36.     Wang, Liqiu; Peng, Xiaojun; Song, Fengling; Lu, Erhu; Cui, Jingnan; Gao, Xinqin; Lu, Rongwen. New near-infrared indocyanines and their spectral properties in SiO2 sol-gel. Dyes and Pigments. 2004, 61(2), 103-107.


  • 教育经历Education Background
  • 工作经历Work Experience
  • 研究方向Research Focus
  • 社会兼职Social Affiliations
  • 有机荧光染料的光物理现象,以及有机荧光染料的生物影像和生物靶标检测的应用
    纳米荧光粒子的制备,以及其在纳米医学领域的应用