孙冰冰，教授，博士生导师。2002、2005年于大连理工大学获得学士、硕士学位，2011年于美国华盛顿大学化学工程系获得博士学位，2011-2016年在美国加州大学洛杉矶分校医学院及加州大学纳米技术环境影响中心从事博士后研究工作。入选国家级青年人才、辽宁省“兴辽计划”青年拔尖人才及大连市高端人才，获中国工程前沿杰出青年学者。致力于生物材料、纳米材料-生物界面、免疫工程、疫苗佐剂、纳米材料生物安全性、以及环境污染物的评价与预防等研究。多学科交叉型的研究涉及了化学工程、生物学、材料学及医学等领域。主持的科研项目包括科技部重点研发计划课题、国家自然科学基金重点基金（联合基金）、国家自然科学基金面上项目及大连市科技创新基金重点学科重大课题等。担任Scientific Reports编委，BMEMat青年编委，中国疫苗行业协会核酸疫苗分会委员及中国细菌感染与疫苗研究专业委员会委员。

指导学生多次获得国家奖学金，致力于本科生培养，多名本科生在读期间以第一作者或参与发表期刊论文。多名本科生、硕士生获得博士全额奖学金, 就读MIT、Northwestern、CUHK等国外一流大学。有广泛的国际高校及知名企业项目合作。

实验室长期招收博士后，请发简历到bingbingsun@dlut.edu.cn。

Publication List:

84. Yao, Z.; Liang, Z.; Li, M.; Wang, H.; Ma, Y.; Guo, Y.; Chen, C.; Xue, C.; Sun, B^*. “Aluminum Oxyhydroxide-Poly(I:C) Combination Adjuvant with Balanced Immunostimulatory Potentials for Prophylactic Vaccines”. Journal of Controlled Release, 2024, 10.1016/j.jconrel.2024.06.054.

83. Li, M.; Yao, Z.; Wang, H.; Ma, Y.; Yang, W.; Guo, Y.; Yu, G.; Shi, W.; Zhang, N.; Xu, M.; Li, X.; Zhao, J.; Zhang, Y.; Xue, C.; Sun, B^*. “Silicon or Calcium Doping Coordinates the Immunostimulatory Effects of Aluminum Oxyhydroxide Nanoadjuvants in Prophylactic Vaccines”. ACS Nano, 2024, doi.org/10.1021/acsnano.4c02685.

82. Li, G.; Dong, Z.; Ren, Q.; Sun, B.; Liu, S.; Ma, J.^*; Zuo, Y.Y.^* “Investigating the Influence of Particle Hydrophobicity on Lung Deposition Using Nonionic Dye Partitioning”. Nano Today, 2024, 57, 102360.

81. Dong, W.; Yan, J.; Ji, T.; Wu, M.; Sun, Y.; He, Y.; Li, X.; Yu, K.; Sun, B.; Liu, Y^*. “Room temperature aqueous synthesis of defect-engineered MOF-801 membrane towards efficient nanofiltration”. Journal of Membrane Science, 2024, 705, 122946.

80. Shi, W.; Sun, S.; Liu, H.; Meng, Y.; Ren, K.; Wang, G.; Liu, M.; Wu, J.; Zhang, Y.; Huang, H.; Shi, M.; Xu, W.; Ma, Q.; Sun, B.; Xu, J^*. “Guiding Bar Motif of Thioredoxin Reductase 1 Modulates Enzymatic Activity and Inhibitor Binding by Communicating with the Co-Factor FAD and Regulating the Flexible C-terminal Redox Motif”. Redox Biology, 2024, 70, 103050.

79. Liu, M.; Sun, S.; Meng, Y.; Wang, L.; Liu, H.; Shi, W.; Zhang, Q.; Xu, W.; Sun, B.; Xu, J^*. “Benzophenanthridine Alkaloid Ahelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-terminal Sec498 Residue of Cytosolic Selenoprotein Thioredoxin Reductase”. Molecules, 2023, 28, 6842.

78. Yan, J.; Sun, Y.; Ji, T.; Wu, M.; Meng, S.; Dong, W.; Liu, Y.; Yu, K.; Hu, W.; Sun, B.; Lu, P.; Li, Y.; Hu, H.^*; Liu, Y.^* “Enhanced CO2/N2 separation in hybrid composite membrane via dispersion of hollow defect-engineered Zr-MOF nanoparticles”. AIChE Journal, 2024, 70:e18426.

77. Chen, C.; Xue, C.; Jiang, J.; Bi, S.; Yu, G.; Sun, B.^*; Mao, C.^* “Neurotoxicity Profiling of Aluminum Salt-Based Adjuvants”. Journal of Pharmacology and Experimental Therapeutics, 2024, doi.org/10.1124/jpet.123.002031.

76. Liang, Z.; Bao, H.; Yao, Z.; Li, M.; Chen, C.; Zhang, L.; Wang, H.; Fu, D.; Yang, X.; Guo, Y.; Yu, G.; Xue, C.^*; Sun, B.^*; Mao, C.^* “The Orientation of CpG Conjugation on Aluminum Oxyhydroxide Nanoparticles Determines the Immunostimulatory Effects of Combination Adjuvants”. Biomaterials, 2024, 308, 122569.

75. Chen, L.; Shao, F.; Chen, K.; Wu, N.; Sun, B.; Ge, D.; Wang, G.; Wang, H.^*; Yang, Q^*. “Organized assembly of chitosan into mechanically strong bio-composite by introducing a recombinant insect structural protein OfCPH-1”. Carbohydrate Polymers, 2024, 334(15), 122044.

74. Chen, C.; Wang, J.; Guo, Y.; Li, M.; Yang, K.; Liu, Y.; Ge, D.; Xue, C.; Xia, T^*; Sun, B^*. “Monosodium Urate Crystals Induced Pyroptotic Cell Death in Neutrophil and Macrophage Facilitates the Pathological Progress of Gout”. Small, DOI: 10.1002/smll.202308749.

73. Yu, G.; Yang, W.; Zhang, N.; Yang, C.; Zeng, H.; Xue, C.^*; Sun, B^*. “Autoclave-Induced Changes in the Physicochemical Properties and Antigen Adsorption of Aluminum Adjuvants”. Journal of Pharmaceutical Sciences, 2024, 113(2), 455-462.

72. Ma, Y.; Guo, Y.; Liu, S.; Hu, Y.; Yang, C.; Cheng, G.; Xue, C.; Zuo, Y.Y.; Sun, B^*. “pH-Mediated Mucus Penetration of Zwitterionic Polydopamine-Modified Silica Nanoparticles”. Nano Letters, 2023, 23(16), 7552-7560.

71. Yan, J.; Sun, Y.; Ji, T.; Liu, Y.; Zhang, N.; Sun, B.; Meng, S.; Yin, B.; Wu, M.; Hu, H^*.; Liu, Y^*. “Facile Synthesis of Oriented Zr–MOF Membrane under Complete Room-Temperature Condition with Superb Selectivity for Carbon Capture”. Industrial & Engineering Chemistry Research, 2023, 62(14), 5973-5983.

70. Guo, Y.; Ma, Y.; Chen, X.; Li, M.; Ma, X.; Cheng, G.; Xue, C.; Zuo, Y.Y.; Sun, B^*. “Mucus Penetration of Surface Engineered Nanoparticles in Various pH Microenvironments”. ACS Nano, 2023, 17, 3, 2813-2828.

69. Xu, X.; Li, G.; Sun, B.; Zuo, Y.Y^*. “S2 Subunit of SARS-CoV-2 Spike Protein Induces Domain Fusion in Natural Pulmonary Surfactant Monolayers”. Journal of Physical Chemistry Letters, 2022, 13, 8359-8364.

68. Wang, S.; Li, Y.; Ding, G.; Li, C.; Zhao, Q.; Sun, B.; Song, Q^*. “Design of UVC Surface Disinfection Robot with Coverage Path Planning Using Map-Based Approach At-The-Edge” Robotics, 2022, 11(6), 117.

67. Fu, D.; Wang, M.; Yang, T.; Li, M.; Liang, Z.; Chen, C.; Zhang, L.; Xue, C.; Sun, B^*, Mao, C^*. “Self-Assembled Flagella Protein Nanofibers Enhance Mucosal Immunity”. Biomaterials, 2022, 288, 121733.

66. Cui, L.; Wang, X.; Zhao, X.; Sun, B.; Xia, T.; Hu, S^*. “CeO₂ nanoparticles induce pulmonary fibrosis via activating S1P pathway as revealed by metabolomics”. Nano Today, 2022, 45, 101559.

65. Bi, S.; Li, M.; Liang, Z.; Li, G.; Yu, G.; Zhang, J.; Chen, C.; Yang, C.; Xue, C.; Zuo, Y.Y.; Sun, B^*. “Self-Assembled Aluminum Oxyhydroxide Nanorices with Superior Suspension Stability for Vaccine Adjuvant”. Journal of Colloid and Interface Science, 2022, 627, 238-246.

64. Chen, C.; Wang, J.; Liang, Z.; Li, M.; Fu, D.; Zhang, L.; Yang, X.; Guo, Y.; Ge, D.; Liu, Y.; Sun, B^*. “Monosodium Urate Crystals with Controlled Shape and Aspect Ratio for Elucidating the Pathological Progress of Acute Gout”. Biomaterials Advances, 2022, 139, 213005.

63. Li, M.; Liang, Z.; Chen, C.; Yu, G.; Yao, Z.; Guo, Y.; Zhang, L.; Bao, H.; Fu, D.; Yang, X.; Wang, H.; Xue, C.; Sun, B^*. “Virus-Like Particle-Templated Silica-Adjuvanted Nanovaccines with Enhanced Humoral and Cellular Immunity”. ACS Nano, 2022, 16(7), 10482-10495.

62. Li, J.; Yu, G.; Liang, Z.; Li, M.; Chen, C.; Zhang, N.; Li, X.; Guo, Y.; Yang, C.; Liu, Y.; Zhang, C.; Zhang, W.; Liu, J.; Ma, X.; Xue, C.; Sun, B^*. “Mechanistic Elucidation of Freezing-Induced Surface Decomposition of Aluminum Oxyhydroxide Adjuvant”. iScience, 2022, 25 (6), 104456.

61. Yu, G.; Liang, Z.; Yu, Z.; Li, M.; Yang, W.; Zhang, Y.; Zhao, Y.; Yang, C.; Xue, C.; Shi, L.; Sun, B^*. “Engineering the Hydroxyl Content on Aluminum Oxyhydroxide Nanorod for Elucidating the Antigen Adsorption Behavior”. npj Vaccines, 2022, 7,62.

60. Liang, Z.; Wang, X.; Yu, G.; Li, M.; Shi, S.; Bao, H.; Chen, C.; Fu, D.; Ma, W.; Xue, C.; Sun, B^*. “Mechanistic Understanding of the Aspect Ratio-Dependent Adjuvanticity of Engineered Aluminum Oxyhydroxide Nanorods in Prophylactic Vaccines”. Nano Today, 2022, 43, 101445.

59. Li, M.; Li. J.; Yang, Y.; Liu, W.; Liang, Z.; Ding, G.; Chen, X.; Song, Q.*; Xue, C.^*; Sun, B^*. “Investigation of Mouse Hepatitis Virus Strain A59 Inactivation Under Both Ambient and Cold Environments Reveals the Mechanisms of Infectivity Reduction Following UVC Exposure”. Journal of Environmental Chemical Engineering, 2022, 10, 107206.

58. Zhang, L.; Liang, Z.; Chen, C.; Yang, X.; Fu, D.; Bao, H.; Li, M.; Shi, S.; Yu, G.; Zhang, Y.; Zhang, C.; Zhang, W.; Xue, C.; Sun, B^*. “Engineered Hydroxyapatite Nanoadjuvants with Controlled Shape and Aspect Ratios Reveal Their Immunomodulatory Potentials”. ACS Applied Materials & Interfaces, 2021, 13(50), 59662-59672.

57. Su, Y.; Liu, T.; Song, C.; Fan, A.; Zhu, N.; Sun, B.; Yang, C^*. “Using MoS2/Fe3O4 as Ion-Electron Transduction Layer to Manufacture All-Solid-State Ion-Selective Electrode for Determination of Serum Potassium”. Chemosensors, 2021, 9(7), 155.

56. Liang, Z.; Yang, Y.; Yu, G.; Zhu, H.; Xia, X.; Chen, C.; Fu, D.; Li, M.; Cheng, G.; Xue, C.; Shi, L.; Zeng, H^*; Sun, B^*. “Engineered Aluminum Phosphate Nanoparticles with Well-Controlled Surface Property as Effective Vaccine Adjuvants”. Biomaterials, 2021, 275, 120960.

55. Liang, Z.; Zhu, H.; Wang, X.; Jing, B.; Li, Z.; Xia, X.; Sun, H.; Yang, Y.; Zhang, W.; Shi, L.; Zeng, H^*; Sun, B^*. “Adjuvants for Coronavirus Vaccines”. Frontiers in Immunology, 2020, 11, 589833.

54. Ma, T.; Wang, X.; Li, L.; Sun, B.; Zhu, Y.^*; Xia, T^*. “Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-κB mediated acute lung inflammation in mice”. Archives of Toxicology, 2020.

53. Shi, S.; Liang, Z.; Sun, B^*. “Response to Comment on: Vaccine Adjuvants: Understanding the Structure and Mechanism of Adjuvanticity”. Vaccine, 2020, 38(13), 2759.

52. Ji, E.; Elzakra, N.; Chen, W.; Cui, L.; Lee, E.; Sun, B.; Messadi, D.; Xia, T.; Zhu Y.; Hu, S^*.“E-cigarette aerosols induce unfolded protein response in normal human oral keratinocytes”. Journal of Cancer, 2019, 10(27), 6915-6924.

51. Cui, L.; Wang, X.; Sun, B.; Xia, T.^*; Hu, S^*. “Predictive Metabolomic Signatures for Safety Assessment of Metal Oxide Nanoparticles”. ACS Nano, 2019, 13(11), 13065-13082.

50. Li, M.; Cheng, F.^*; Xue, C.; Wang, H.; Chen, C.; Du, Q.; Ge, D.; Sun, B^*. “Surface Modification of Stöber Silica Nanoparticles with Controlled Moiety Densities Determines Their Cytotoxicity”. Langmuir, 35(45), 14688-14695.

49. Feng, Y.; Wang, L.; Chang, Y.; Cheng, Y.; Sun, B.; Wang, L.^*; Chen, C.; Zhang, H^*. “Electron Compensation Effect Suppressed Silver Ion Release and Contributed Safety of Au@Ag Core–Shell Nanoparticles”. Nano Letters, 2019, 19 (7), 4478-4489. 

48. Du, Q.; Ge, D.; Vahid, M.; Chen, C.; Li, M.; Xue, C.; Ma, X.; Sun, B^*. “Assessment of Neurotoxicity Induced by Different-Sized Stöber Silica: Induction of Pyroptosis in Microglia”. Nanoscale, 2019, 11, 12965-12972.

47. Ge, D.; Du, Q.; Ran, B.; Liu, X.; Wang, X.; Ma, X.; Cheng, F.; Sun, B^*. “The Neurotoxicity Induced By Engineered Nanomaterials” International Journal of Nanomedicine, 2019, 14, 4167-4186.

46. Shi, S.; Zhu, H.; Xia, X.; Liang, Z.; Ma, X.; Sun, B.^* "Vaccine Adjuvants: Understanding the Structure and Mechanism of Adjuvanticity". Vaccine, 2019, 37 (24), 3167-3178.

45. Cheng, F.^*; Wang, H.; He, W.; Sun, B.; Zhao, J.; Qu, J; Wang, Q.“New Strategy for Functionalization of Silica Materials viaCatalytic Oxa-Michael Reaction of Surface Silanol Groups with Vinyl Sulfones”. ACS Sustainable Chemistry & Engineering, 2019, 7 (10), 9112-9120.

44. Cheng, F.^*; Li, M.; He, W.; Sun, B.; Qin, J.; Qu, J.“Activation of Resin with Controllable Ligand Density via Catalytic oxa-Michael Addition and Application in Antibody Purification”. Journal of Chromatography A, 2018, 1570 (5), 1-9.

43. Mirshafiee, V*.; Sun, B.*; Chang, C.H.; Jiang, W.; Jiang, J.; Liu, X.; Liao Y.-P.; Wang, X.; Nel, A.E.; Xia, T. “Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages versus Apoptosis in Hepatocytes”. ACS Nano, 2018, 12 (4), 3836-3852. *Equal contribution.

42. Li, R.; Guiney, L.; Chang, C.H.; Mansukhani, N.; Ji, Z.; Wang, X.; Liao Y.-P.; Jiang, W.; Sun, B.; Hersam, M.; Nel, A.; Xia, T. “The Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model”. ACS Nano, 2018, 12 (2), 1390-1402.

41. Lu, J.; Liu, X.; Liao Y.-P.; Bergara, F.; Sun, B.; Jiang, W.; Chang, C.H., Jiang, J.; Wang, X.; Wu, A.; Meng, H.; Nel, A.E. “Nano-enabled Pancreas Cancer Immunotherapy using Immunogenic Cell Death and Reversing Immunosuppression”. Nature Communications, 2017, DOI: 10.1038/s41467-017-01651-9.

40. Sun, B.*; Ji, Z.; Liao, Y.-P.; Chang, C.H.; Justine, K.; Wang, X.; Mirshafiee, V.; Xue, C.; Xia, T*. “Enhanced immune adjuvant activity of aluminum oxyhydroxide nanorods through cationic surface functionalization”. ACS Applied Materials & Interfaces, 2017, 9 (26), 21697-21705. *Corresponding author. 

39. Mirshafiee, V.; Jiang, W.; Sun, B.; Wang, X.; Xia, T. “Facilitating translational nanomedicine via predictive safety assessment”. Molecular Therapy, 2017, 25 (7), 1522-1530. 

38. Wang, X.*; Sun, B.*; Liu, S.; Xia, T. “Structure activity relationships of engineered nanomaterials in inducing NLRP3 inflammasome activation and chronic lung fibrosis”. NanoImpact, 2017, 6, 99-108. *Equal contribution. 

37. Jiang, W.; Wang, X.; Du, Y.; Chang, C.H.; Liao, Y-P.; Osberne, O.; Sun, B.; Jiang, J.; Ji, Z.; Li, R.; Liu, X.; Lu, J.; Lin, S.; Meng, H.; Xia, T.; Nel, A.E. “Pro-inflammatory and pro-fibrogenic effects of ionic and particulate arsenide and indium-containing semiconductor materials in the murine lung”. ACS Nano, 2017, 11 (2), 1869-1883. 

36. Chen, Y.; Wu, Y.; Sun, B.; Liu, S; Liu, H. “Two-dimensional nanomaterials for cancer nanotheranostics”. Small, 2017, 13 (10), 1603446. 

35. Sun, B.; Wang, X.; Liao, Y.-P.; Ji, Z.;  Chang, C.H.; Pokhrel, S.; Justine, K.; Liu, X.; Wang, M.; Dunphy, D.; Li, R.; Meng, H.; Mädler, L.; Brinker, C.J.; Nel, A.E.; Xia, T. “Repetitive dosing of fumed silica leads to profibrogenic effects through unique structure-activity relationships and biopersistence in the lung”. ACS Nano, 2016, 10 (8), 8054-8066. 

34. Sun, B.*; Xia, T. “Nanomaterial-based vaccine adjuvants”. Journal of Materials Chemistry B, 2016, 4, 5496-5509. *Corresponding author. 

33. Ji, E.H.*; Sun, B.*; Zhao, T.; Shu, S.; Chang, C.H.; Messadi, D.; Xia, T.; Zhu, Y.; Hu, S. “Characterization of electronic cigarette aerosol and its induction of oxidative stress response in oral keratinocytes”. PLOS ONE, 2016, 11(5): e0154447. *Equal contribution. Highlighted by UCLA Newroom, Mynewsla, abc7, MedlinePlus (NIH), Medicalnewstoday, Medicalxpress, etc. 

32. Wang, X.; Mansukhani, N.; Guiney, L.; Lee, J.-H.; Li, R.; Sun, B.; Liao, Y.-P.; Chang, C.H.; Ji, Z.; Xia, T.; Hersam, M.C.; Nel, A.E. “Toxicological profiling of highly-purified metallic and semiconducting single-walled carbon nanotubes in the rodent lung and E. coli”. ACS Nano, 2016, 10 (6), 6008–6019. 

31. Liu, J.; Sun, B.; Yin, H.; Liu, S. “Hepcidin: a promising therapeutic target for iron disorders”. Medicine, 2016, 95(14), e3150. 

30. Sun, B.; Taing, A.; Liu, H.; Nie, G.; Wang, J.; Fang, Y.; Liu, L.; Xue Y., Liao, Y.-P.; Ku, J.; Xia, T.; Liu, Y. “Nerve growth factor-conjugated mesoporous silica nanoparticles promote neuron-like PC12 cell proliferation and neurite growth”. Journal of Nanoscience and Nanotechnology, 2016, 16 (3), 2390-2393. 

29. Sun, B.; Shen, H. “Controlling surface-induced nanocomposites by lipoplexes for enhanced gene transfer”. Journal of Nanomaterials, 2015, 784836. 

28. Jiang, W.; Lin, S.; Chang, C.H.; Ji, Z.; Sun, B.; Wang, X.; Li, R.; Pon, N.; Xia, T.; Nel, A.E. “Implications of the differential toxicological effects of III-V ionic and particulate materials for hazard assessment of semiconductor slurries”. ACS Nano, 2015, 9 (12), 12011-12025. 

27. Sun, B.; Pokhrel, S.; Dunphy, D.; Zhang, H.; Ji, Z.; Wang, X.; Wang, M.; Liao, Y.-P.; Chang, C.H.; Dong, J.; Li, R.; Mädler, L.; Brinker, C.J.; Nel, A.E.; Xia, T. “Reduction of acute inflammatory effects of fumed silica nanoparticles in the lung by adjusting silanol display through calcination and metal doping”. ACS Nano, 2015, 9 (9), 9357-9372. Highlighted by ACS Nanotation. 

26. Wang, X.; Mansukhani, N.; Guiney, L.; Ji, Z.; Chang, C.H.; Wang, M.; Liao, Y.-P.; Song, T.-B., Sun, B.; Li, R.; Xia, T.; Hersam, M.C.; Nel, A.E. “Differences in the toxicological potential of two-dimensional versus aggregated molybdenum disulfide in the lung”. Small, 2015, 11 (38), 5079-5087. 

25. Sun, B.; Shen, H. “Correlation of the composition of biominerals with their ability of stimulating intracellular DNA sensors and inflammatory cytokines”. Biomaterials, 2015, 54, 106-115. Highlighted by Nanowerk. 

24. Li, R.; Ji, Z.; Dong, J.; Chang, C.H.; Wang, X.; Sun, B.; Wang, M.; Liao, Y.-P.; Zink, J.; Nel, A.E.; Xia, T. “Enhancing the imaging and biosafety of upconversion nanoparticles through phosphonate coating”. ACS Nano, 2015, 9 (3), 3293–3306. 

23. Tang, Q.; Lei, X.; Cao, B.; Sun, B.; Zhang, Y.; Cheng, G. “A naturally derived dextran-peptide vector for microRNA antagomir delivery”. RSC Advances, 2015, 5, 28019-28022. 

22. Wang, X.; Duch, M.; Mansukhani, N.; Ji, Z; Liao, Y.-P.; Wang, M.; Zhang, H.; Sun, B.; Chang, C.H.; Li, R; Lin, S.; Meng, H.; Xia, T.; Hersam, M.C.; Nel, A.E. “Use of a predictive toxicological approach that utilizes the pro-fibrogenic effects of carbon nanotubes and graphene for tiered decision analysis of testing requirements for carbon-based nanomaterials”. ACS Nano, 2015, 9 (3), 3032–3043. 

21. Sun, B.; Wang, X.; Ji, Z.; Wang, M.; Liao, Y.-P.; Chang, C.H.; Li, R.; Zhang, H.; Nel, A.E.; Xia, T. “NADPH oxidase dependent NLRP3 inflammasome activation plays an important role in lung fibrosis by multi-walled carbon nanotubes”. Small, 2015, 11 (17), 2087-2097. Highlighted by MaterialsViewsChina. 

20. Li, R.; Ji, Z.; Qin, H.; Kang, X.; Sun, B.; Wang, M.; Chang, C.H.; Wang, X.; Zhang, H.; Zou, H.; Nel, A.E.; Xia, T. “Interference in autophagosome fusion by rare earth nanoparticles disrupts autophagic flux and regulation of an interleukin-1β producing inflammasome”. ACS Nano, 2014, 8 (10), 10280-10292. 

19. Tang, Q.; Cao, B.; Lei, X.; Sun, B.; Zhang, Y.; Cheng, G. “Dextran-peptide hybrid for efficient gene delivery”. Langmuir, 2014, 30 (18), 5202-5208. 

18. Zhang, H.; Pokhrel, S.; Ji, Z.; Meng, H.; Wang, X.; Lin, S.; Chang, C.H.; Li, L.; Li, R.; Sun, B.; Wang, M.; Liao, Y.-P.; Liu, R.; Xia, T.; Mädler, L.; Nel, A.E. “PdO doping tunes band-gap energy levels as well as oxidative stress responses to a Co3O4 p-type semiconductor in cells and the lung”. Journal of the American Chemical Society, 2014, 136 (17), 6406-6420. 

17. Li, R.; Ji, Z.; Chang, C.H.; Dunphy, D.; Cai, X.; Meng, H.; Zhang, H.; Sun, B.; Wang, X.; Dong, J.; Lin, S.; Wang, M.; Liao, Y.-P.; Brinker, C.J.; Nel, A.E.; Xia, T. “Surface interactions with compartmentalized cellular phosphates explains rare earth oxide nanoparticle hazard and provides opportunities for safer design”. ACS Nano, 2014, 8 (2), 1771-1783. 

16. Cao, B.; Li, L.; Wu, H.; Tang, Q.; Sun, B.; Dong, H.; Zhe, J.; Cheng, G. “Zwitteration of dextran: a facile route to integrate antifouling, switchability and optical transparency into natural polymers”. Chemical Communications, 2014, 50, 3234-3237. 

15. Wang, X.; Ji, Z.; Chang, C.H.; Zhang, H.; Lin, S.; Meng, H.; Wang, M.; Liao, Y.-P.; Li, R.; Sun, B.; Van Winkle, L.S.; Pinkerton, K.; Zink, J.; Xia, T.; Nel, A.E. “Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential”. Small, 2014, 10 (2), 385-398. 

14. Sun, B.; Ji, Z.; Liao, Y.-P.; Wang, M.; Wang, X.; Dong, J.; Chang, C.H.; Li, R.; Nel, A.E.; Xia, T. “Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles”. ACS Nano, 2013, 7 (12), 10834-10849. Highlighted as Key Scientific Article by Global Medical Discovery. 

13. Sun, B.; Wang, X.; Li, R.; Ji, Z.; Xia, T. “NLRP3 inflammasome activation induced by engineered nanomaterials”. Small, 2013, 9 (9-10), 1595-1607. 

12. Sun, B.; Li, R.; Wang, X.; Xia, T. “Predictive toxicological paradigm and high throughput approach for toxicity screening of engineered nanomaterials”. International Journal of Biomedical Nanoscience and Nanotechnology, 2013, 3 (1-2), 4-18. 

11. Qu G.; Liu, S.; Zhang, S.; Wang, L.; Wang, X.; Sun, B.; Yin, N.; Gao, X.; Xia, T.; Chen, J.; Jiang, G. “Graphene oxide induces Toll-like receptor 4 (TLR4)-dependent necrosis in macrophages”. ACS Nano, 2013, 7 (7), 5732 - 5745. 

10. Li, R.; Wang, X.; Ji, Z.; Sun, B.; Zhang, H.; Chang, C.H.; Lin, S.; Meng, H.; Liao, Y.-P.; Wang, M.; Li, Z.; Hwang, A.A.; Song, T.-B.; Xu, R.; Yang, Y.; Zink, J.; Nel, A.E.; Xia, T. “Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity”. ACS Nano, 2013, 7 (3), 2352-2368. 

9. Zhang, H.; Dunphy, D.; Jiang, X.; Meng, H.; Sun, B.; Tarn, D.; Xue, M.; Wang, X.; Lin, S.; Ji, Z.; Li, R.; Garcia, F.; Yang, J.; Kirk, M.; Xia, T.; Zink, J.; Nel, A.E.; Brinker, C.J. “Processing pathway dependence of amorphous silica nanoparticle toxicity - colloidal versus pyrolytic”. Journal of the American Chemical Society, 2012, 134 (38), 15790-15804. 

8. Ji, Z.; Wang, X.; Zhang H.; Lin, S.; Meng, H.; Sun, B.; George, S.; Xia, T.; Nel, A.E.; Zink, J. “Designed synthesis of CeO2 nanorods and nanowires for studying toxicological effects of high aspect ratio materials”. ACS Nano, 2012, 6 (6), 5366-5380. 

7. Wang, X.; Xia, T.; Duch, M.; Ji, Z.; Zhang, H.; Li, R.; Sun, B.; Lin, S.; Meng, H.; Liao, Y.-P.; Wang, M.; Song, Z.-B.; Yang, Y.; Hersam, M.C.; Nel, A.E. “Pluronic F108 coating decreases the lung fibrosis potential of multiwall carbon nanotubes by reducing lysosomal injury”. Nano Letters, 2012, 12 (6), 3050-3061. 

6. Sun, B.; Yi, M.; Yacoob, C.; Nguyen, H.; Shen, H. “Effect of surface chemistry on gene transfer efficiency mediated by surface-induced DNA-doped nanocomposites”. Acta Biomaterialia, 2012, 8 (3), 1109-1116. 

5. Nguyen, H.; Tran, K.K.; Sun, B.; Shen, H. “Activation of inflammasomes by tumor cell death mediated by gold nanoshells”. Biomaterials, 2012, 33 (7), 2197-2205. 

4. Chen, H.; Sun, B.; Tran, K.K.; Shen, H. “Effects of particle size on toll-like receptor 9-mediated cytokine profiles”. Biomaterials, 2011, 32 (6), 1731-1737. 

3. Sun, B.; Tran, K.K.; Shen, H. “Enabling customization of non-viral gene delivery systems for individual cell types by surface-induced mineralization”. Biomaterials, 2009, 30 (31), 6386-6393. 

2. Chen, H.-H.; Sun, B.; Tran, K.K.; Shen, H.; Gao, D. “A microfluidic manipulator for enrichment and alignment of moving cells and particles”. Journal of Biomechanical Engineering, 2009, 131 (7), 074505. 

1. Ma, X.; Sun, B.; Liu, T.; Cui, Z. “Study of microscopic experiment for freezing/vitrifying characteristics of CPA solution and cell suspension”. Journal of Dalian University of Technology, 2005, 45 (4), 517-521.

实验室座右铭：创新、协作、诚信、责任；Innovation, Teamwork, Integrity, Responsibility.

实验室毕业生：

Zexiao Hao, M.S. in Chemical Engineering (2024), Now at SiEn (QingDao) Integrated Circuits Co., Ltd. 

Jiashu Zhao, M.S. in Chemical Engineering (2024), Now at SINOPEC YIZHENG CHEMICAL FIBRE CO. , LTD.

Hongyang Gao, M.S. in Chemical Engineering (2024), Now at MFLEX Suzhou Co., Ltd

Xiaoyu Zhang, M.S. in Chemical Engineering (2024), Now at Sinopec Economics & Development Research Institute Company Limited.

Yubin Ma, M.S. in Chemical Engineering (2024), Now at The Chinese University of Hong Kong.

Yuhang Yuan, B.S. in Chemical Engineering (2024), Now at Dalian University of Technology.

Chaoyang Gong, B.S. in Chemical Engineering (2024), Now at Dalian University of Technology.

Wendi Shi, B.S. in Chemical Engineering (2024), Now at Dalian University of Technology.

Zhili Wang, B.S. in Chemical Engineering (2024), Now at Dalian University of Technology.

Mingyang Han, B.S. in Chemical Engineering (2024), Now at Sichuan University.

Yiheng Qiu, B.S. in Chemical Engineering (2024), Now at Dalian University of Technology.

Tongyu Wu, B.S. in Chemical Engineering (2024), Now at National University of Singapore.

Min Li, Ph.D. in Chemical Engineering (2024), Now at The Chinese University of Hong Kong.

Ge Yu, Ph.D. in Chemical Engineering (2024), Now at Changchun BCHT Biotechnology Co.

Chen Chen, Ph.D. in Bioengineering (2023), Now at Yantai Institute of Pharmaceutical Science.

Kaijie Qin, M.S. in Chemical Engineering (2023), Now at Hangzhou Fullsemi Semiconductor Co., Ltd.

Jiaxuan Jiang, M.S. in Chemical Engineering (2023), Now at Shanghai Nuclear Engineering Research and Design Institute Co., Ltd.

Sensen Wang, M.S. in Chemical Engineering (2023), Now at BYD Company Limited.

Nan Zhang, M.S. in Chemical Engineering (2023), Now at Beijing Yanshan Petrol-Chemical Industry Co., Ltd.

Mengwei Liu, M.S. in Chemical Engineering (2023), Now at Hengli Petrochemical (Huizhou) Co., Ltd.

Zhihao Hou, M.S. in Chemical Engineering (2023), Now at Wanhua Chemical Group Co., Ltd.

Yue Zhang, B.S. in Chemical Engineering (2023), Now at Dalian University of Technology.

Yu Hu, B.S. in Chemical Engineering (2023), Now at Dalian University of Technology.

Haocheng Sun, B.S. in Chemical Engineering (2023), Now at Dalian University of Technology.

Qinlin Sun, B.S. in Chemical Engineering (2023), Now at Dalian University of Technology.

Han Wang, B.S. in Fine Chemical Engineering (2023), Now at Tianjin University.

Meng Wang, B.S. in Chemical Engineering (2023), Now at Institute of High Energy Physics, Chinese Academy of Sciences.

Yuhan Zhang, B.S. in Chemical Engineering (2023), Now at Dalian University of Technology.

Zhihui Liang, Ph.D. in Chemical Engineering (2022), Now at The Chinese University of Hong Kong.

Shisheng Bi, M.S. in Chemical Engineering (2022), Now at Getein Biotech, Inc.

Jiahuan Li, M.S. in Chemical Engineering (2022), Now at GeneScience Pharmaceuticals Co., Ltd. (GenSci).

Han Xiao, B.S. in Chemical Machinery (2022), Now at Tsinghua University.

Zhenwei Wu, B.S. in Chemical Engineering (2022), Now at Northwestern University (USA).

Huiyang Wang, B.S. in Chemical Engineering (2022), Now at Dalian University of Technology.

Xin Li, B.S. in Chemical Engineering (2022), Now at Dalian University of Technology.

Jiarui Zhang, M.S. in Chemical Engineering (2021), Now at Intel Semiconductor (Dalian) Co.

Xingjuan Guo, M.S. in Chemical Engineering (2021), Now at Sinovac (Dalian) Vaccine Technology Co., Ltd.

Lei Zhang, M.S. in Chemical Engineering (2021), Now at Hangzhou Valgen Medtech Co., Ltd.

Jiaqi Zhang, B.S. in Chemical Engineering (2021), Now at Stanford University (USA).

Yixuan Zhang, B.S. in Chemical Engineering (2021), Now at Imperial College London.

Zilan Yu, B.S. in Chemical Engineering (2021), Now at Fudan University.

Zifan Li, B.S. in Chemical Engineering (2021), Now at Zhejiang University.

Xin Wang, B.S. in Chemical Engineering (2021), Now at National Center for Nanoscience and Technology.

Yubin Ma, B.S. in Chemical Engineering (2021), Now at Dalian University of Technology.

Zhiying Yao, B.S. in Chemical Engineering (2021), Now at Dalian University of Technology.

Shuting Shi, B.S. in Chemical Engineering (2020), Now at Massachusetts Institute of Technology (USA).

Haoru Zhu, B.S. in Chemical Engineering (2020), Now at Zhejiang University.

Xinyu Xia, B.S. in Chemical Engineering (2020), Now at Zhejiang University.

Bo Jing, B.S. in Chemical Engineering (2020), Now at Tianjin University.

Yuhang Zhao, B.S. in Chemical Engineering (2020), Now at National University of Defense Technology.

Aiqiao Fan, B.S. in Chemical Engineering (2020), Now at Dalian University of Technology.

Qiqi Du, M.S. in Chemical Engineering (2019), Now at Pfizer, Dalian.

Jiajie Li, B.S. in Polymer Science (2019), Now at University of California, San Diego (USA).

Xuanxuan Tang, B.S. in Chemical Engineering (2019), Now at University of Manchester.

Yawei Zhang, B.S. in Chemical Engineering (2019), Now at National University of Singapore.

Yutong Chen, B.S. in Chemical Engineering (2019), Now at University of Manchester.

Han Zhang, B.S. in Pharmaceutical Science (2018), Now at National University of Singapore.

Zhe Jiang, B.S. in Chemical Engineering (2018), Now at Northeastern University, China.

La Zhuo, B.S. in Chemical Engineering (2018), Now at University of Sheffield.