孙亚琴

个人信息Personal Information

副教授

博士生导师

硕士生导师

性别:女

毕业院校:大连理工大学

学位:博士

所在单位:生物工程学院

学科:生物化工

电子邮箱:sunyaqin@dlut.edu.cn

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Sugaring-out extraction coupled with fermentation of lactic acid

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论文类型:期刊论文

发表时间:2016-03-17

发表刊物:SEPARATION AND PURIFICATION TECHNOLOGY

收录刊物:SCIE、EI

卷号:161

页面范围:152-158

ISSN号:1383-5866

关键字:Lactic acid; Sugaring-out extraction; Fermentation; Sugar-based chemicals

摘要:Sugaring-out extraction as a novel phase separation for sugar-based chemicals was postulated to extract lactic acid from the fermentation broth by means of sugars and organic solvents. From the different sugaring-out extraction systems investigated, the isopropanol glucose system was found to be more favorable. The partition coefficient (1.39) and recovery (84.27%) of lactic acid were obtained by a system consisting of 12% (w/w) glucose and 40% (w/w) isopropanol. The glucose-rich bottom phase can be utilized to produce lactic acid after recovery of isopropanol. The experimental results were comparable with the normal fermentation, e.g. the yield of lactic acid to glucose being 91.1% vs. 94.0%. This provides a novel approach to integrate sugaring-out extraction into fermentation for production of sugar-based chemicals. (C) 2016 Elsevier B.V. All rights reserved.