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个人信息Personal Information
高级工程师
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学
办公地点：理工西部校区实验楼F308
联系方式：rzhang@dlut.edu.cn
电子邮箱：rzhang@dlut.edu.cn
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Highly efficient Cu(I)-catalyzed trifluoromethylation of aryl(heteroaryl) enol acetates with CF3 radicals derived from CF3SO2Na and TBHP at room temperature
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论文类型：期刊论文
发表时间：2014-05-01
发表刊物：JOURNAL OF FLUORINE CHEMISTRY
收录刊物：SCIE
卷号：161
页面范围：128-133
ISSN号：0022-1139
关键字：Trifluoromethylation; Enol acetates; Synthetic methods; alpha-CF3 ketone; Radical addition
摘要：An efficient method for the Cu(I)-catalyzed synthesis of a-trifluoromethyl ketones via the addition of CF3 to aryl(heteroaryl) enol acetates by using the readily available CF3SO2Na (Langlois reagent) has been developed. The reaction is experimentally simple and carried out at room temperature, providing good to excellent yields with wide functional group tolerance. (C) 2014 Elsevier B.V. All rights reserved.