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论文类型：期刊论文
发表时间：2016-04-01
发表刊物：PACIFIC JOURNAL OF OPTIMIZATION
收录刊物：SCIE
卷号：12
期号：2,SI
页面范围：437-449
ISSN号：1348-9151
关键字：batch culture; optimal control; multistage nonlinear dynamical system; swarm intelligence algorithm
摘要：We propose an optimal control formulation of the batch culture of glycerol bio-dissimilation to 1,3-propanediol (1,3-PD) in industrial production, a gradient-based optimization algorithm is developed to solve the problem. Since the algorithm needs to solve state and costate differential equations simultaneously, and the solution may be trapped at a local one, in this paper, based on the theory of swarm intelligence algorithm, together with the time-scaling transformation and smoothing technique, we propose a modified particle swarm algorithm to solve the optimal control problem. Numerical results show that by employing the optimal control strategy, the concentration of 1,3-PD at the terminal time is higher compared with the previous results.