点击次数：
论文类型：期刊论文
发表时间：2012-01-01
发表刊物：APPLIED MATHEMATICAL MODELLING
收录刊物：SCIE、EI
卷号：36
期号：1
页面范围：357-369
ISSN号：0307-904X
关键字：Fed-batch culture; Logic control; Nonlinear hybrid system; Parameter identification; Asynchronous parallel PSO algorithm
摘要：In this paper, we study the fed-batch fermentation of glycerol by Klebsiella pneumoniae with open loop glycerol input and pH logic control using a flow of alkali as manipulated variable. A nonlinear hybrid system is developed to describe this process. We prove the finiteness of switching numbers of the system in terms of bounded variation and explore the existence and uniqueness of the solutions. Additionally, a parameter identification problem is proposed and an asynchronous parallel particle swarm optimization (PSO) algorithm is constructed to solve it. Numerical results show the effectiveness of the algorithm and reveal that the proposed model could describe the fed-batch process properly. (C) 2011 Elsevier Inc. All rights reserved.