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Synthesis of 4-Substituted Styrene Compounds via Palladium-Catalyzed Suzuki Coupling Reaction Using Free Phosphine Ligand in Air

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Indexed by:期刊论文

Date of Publication:2010-01-01

Journal:SYNTHETIC COMMUNICATIONS

Included Journals:SCIE

Volume:40

Issue:2

Page Number:196-205

ISSN No.:0039-7911

Key Words:4-Substituted styrene compounds; Schiff base ligands; Suzuki; synthesis

Abstract:The air-stable and easy to prepare nonsymmetric Schiff base ligands have been synthesized and proven to be efficient ligands for Suzuki cross-coupling reaction between aryl bromides and arylboronic acids using PdCl2(CH3CN)2 as palladium source under aerobic conditions. The coupling reaction proceeded smoothly using N-[(3,4-dimethoxyphenyl)methylene]-1,2-benzenediamine (L3) as ligand under mild conditions to provide 4-substituted styrene compounds in good yields.

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