点击次数：

论文类型：期刊论文

发表时间：2014-01-01

发表刊物：ABSTRACT AND APPLIED ANALYSIS

收录刊物：SCIE

ISSN号：1085-3375

摘要：In this paper a HBV infection model with impulsive vaccination is considered. By using fixed point theorem and stroboscopic map we prove the existence of disease-free T-periodic solution. Also by comparative theorem of impulsive differential equation we get the global asymptotic stability of the disease-free periodic solution and permanence of the disease. Numerical simulations show the influence of parameters on the dynamics of HBV, which provided references for seeking optimal measures to control the transmission of HBV.