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Indexed by:期刊论文

Date of Publication:1999-01-01

Journal:Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities

Included Journals:PKU、Scopus

Volume:20

Issue:4

Page Number:571-572

ISSN No.:02510790

Abstract:The synthetic method for 2-(2-bromophenyl)oxazoline was modified. The condensation reaction of N-(  -hydroxyethyl)-o-bromobenzamide to corresponding oxaozoline is performed by using SOCl2, not NaH reagent, with a elevated yield of up to 84%. The experimental results show that the reaction temperature has a great influence on the oxazoline yield. The oxazoline yield drop obviously with the rising of the reaction temperature and at room temperature hardly any oxazoline product formed. Based on the results obtained, it is presumed that ehe oxazoline ring was formed via an imide tautermer intermediate.