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论文类型：期刊论文

发表时间：1999-01-01

发表刊物：Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities

收录刊物：PKU、Scopus

卷号：20

期号：4

页面范围：571-572

ISSN号：02510790

摘要：The synthetic method for 2-(2-bromophenyl)oxazoline was modified. The condensation reaction of N-(  -hydroxyethyl)-o-bromobenzamide to corresponding oxaozoline is performed by using SOCl2, not NaH reagent, with a elevated yield of up to 84%. The experimental results show that the reaction temperature has a great influence on the oxazoline yield. The oxazoline yield drop obviously with the rising of the reaction temperature and at room temperature hardly any oxazoline product formed. Based on the results obtained, it is presumed that ehe oxazoline ring was formed via an imide tautermer intermediate.