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Date of Publication:2011-01-01

Journal:功能材料

Issue:1

Page Number:43-46

ISSN No.:1001-9731

Abstract:Poly(lactide-co-glycolide) (PLGA) 50/50 and 75/25 were applied as materials, and films were prepared by casting method. The PLGA films included PLGA 50/50 single-component films, PLGA 75/25 single-component films, blended films of two kind of PLGAs, and gradient films with non-uniform component distribution. The four types of PLGA films were immersed in pH7.4 phosphate buffered saline at 37°C. The properties of these PLGA films such as molecular weight, mass loss, water absorption, pH value, and morphology were analyzed during degradation process. The results showed that the PLGA gradient films had the stablest degradation properties.

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