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个人信息Personal Information
教授
博士生导师
硕士生导师
性别:男
毕业院校:大连理工大学
学位:博士
所在单位:化工学院
学科:化学工程. 生物医学工程
办公地点:1. 西部校区D段楼305
2. 环境生命楼3-403
联系方式:Email: liutq@dlut.edu.cn QQ: 343028655
电子邮箱:liutq@dlut.edu.cn
Hematopoietic stem cells: multiparameter regulation
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论文类型:期刊论文
发表时间:2016-04-01
发表刊物:HUMAN CELL
收录刊物:SCIE、PubMed
卷号:29
期号:2
页面范围:53-57
ISSN号:1749-0774
关键字:Hematopoietic stem cells (HSCs); Ex vivo expansion; Multiparameter regulation
摘要:Hematopoietic stem cells (HSCs) are capable to self-renew with multi-potency which generated much excitement in clinical therapy. However, the main obstacle of HSCs in clinical application was insufficient number of HSCs which were derived from either bone marrow, peripheral blood or umbilical cord blood. This review briefly discusses the indispensable utility of growth factors and cytokines, stromal cells, extracellular matrix, bionic scaffold and microenvironment aiming to control the hematopoiesis in all directions and provide a better and comprehensive understanding for in vitro expansion of hematopoietic stem cells.
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