Release Time:2019-03-11  Hits:

Indexed by: Journal Article

Date of Publication: 2009-06-25

Journal: 化学与生物工程

Included Journals: ISTIC

Volume: 26

Issue: 6

Page Number: 48-50

ISSN: 1672-5425

Key Words: 马来酸桂哌齐特;冷冻干燥;稳定性;赋形剂

Abstract: 采用浓度为80 g·L-1的马来酸桂哌齐特溶液制备冻干制剂.结果表明,甘露醇为赋形剂时冻干制剂稳定性最好,在甘露醇浓度为160 g·L-1时制备的马来酸桂哌齐特冻干制剂主体含量≥99.0%、杂质含量≤0.2%、平均含水量≤1.0%.