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马来酸桂哌齐特冻干制剂制备及质量稳定性研究

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Indexed by:期刊论文

Date of Publication:2009-06-25

Journal:化学与生物工程

Included Journals:ISTIC

Volume:26

Issue:6

Page Number:48-50

ISSN No.:1672-5425

Key Words:马来酸桂哌齐特;冷冻干燥;稳定性;赋形剂

Abstract:采用浓度为80 g·L-1的马来酸桂哌齐特溶液制备冻干制剂.结果表明,甘露醇为赋形剂时冻干制剂稳定性最好,在甘露醇浓度为160 g·L-1时制备的马来酸桂哌齐特冻干制剂主体含量≥99.0%、杂质含量≤0.2%、平均含水量≤1.0%.

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