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论文类型：期刊论文

发表时间：2022-06-28

发表刊物：过程工程学报

卷号：12

期号：6

页面范围：996-1001

ISSN号：1009-606X

摘要：A substrate feeding strategy was studied in the fed-batch fermentation
   of 1,3-propanediol by Klebsiella pneumoniae, which was distinctively
   coupled with cell growth and metabolism using glycerol as substrate. The
   functional relationship between substrate consumption, biomass and
   alkaline consumption was established by analysis of the cell growth
   kinetics during logarithmic growth and stationary phase, respectively.
   The fed-batch on-line experimental results showed that the glycerol
   concentration was controlled at 202 g/L, and the final 1,3-propanediol
   concentration reached 80.3 and 78.8 g/L, which increased 25.0 and 23.5
   g/L compared with that of manual feeding-back strategy.

备注：新增回溯数据