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论文类型：期刊论文

发表时间：2013-07-01

发表刊物：BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

收录刊物：Scopus、PubMed、EI、SCIE

卷号：60

期号：4

页面范围：430-435

ISSN号：0885-4513

关键字：continuous cultures; time-delay system; LMIs; feedback control

摘要：In this paper, stability analysis and controller design in microbial continuous culture with discrete time delay are studied. The dissimilation process of glycerol to 1,3-propanediol cannot avoid the disturbances caused by time delay. Time delay can limit and degrade the achievable performance of controlled systems, and even induce instability. Based on the biodynamic model, some properties of its solutions are discussed. In addition, we investigate how the time-delay affects the stability of the system. A linear matrix inequalities method is applied to find a feedback controller to ensure the stability of the closed-loop system. The simulation results indicate that this controller might be feasible for continuous bioprocess control.