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发表时间：2022-10-04

发表刊物：计算力学学报

期号：2

页面范围：269-273,279

ISSN号：1007-4708

摘要：The therapy of disease‐related molecular network is usually based on the multiple target drug therapy .The multiple target drug therapy can be divided into two steps .First ,filtering the potential drug targets .Second ,making use of them to compose ,in order to find the effective inhibition scheme . However ,the present algorithm takes too much time .This article used the Arachidonic acid inflammation metabolic network as a concrete example ,and also used the improved parallel particle swarm optimization to optimize the multiple targets .As a result ,it can not only compose the drug targets effectively ,but also save more time than the present algorithm according to the number of processes .

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