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个人信息Personal Information
教授
博士生导师
硕士生导师
任职 : 基础化学实验中心主任
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：化学学院
学科：有机化学
办公地点：化工综合楼C503
联系方式：13998559668
电子邮箱：jiangwf@dlut.edu.cn
Facile synthesis of amide and amine derivatives of 2,2,3,3-tetramethylcyclopropanecarboxylic acid
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论文类型：期刊论文
发表时间：2009-08-01
发表刊物：JOURNAL OF CHEMICAL RESEARCH-S
收录刊物：SCIE
期号：8
页面范围：508-510
ISSN号：0308-2342
关键字：2,2,3,3-tetramethylpropanecarboxylic acid; N,N-dimethylacetamide; reduction reaction; TiCl(4)/NaBH(4)
摘要：An efficient one-pot procedure for the synthesis of amide derivatives of 2,2,3,3-tetramethylpropanecarboxylic acid (TMCA) that involves the treating of TMCA in N,N-dimethylacetamide (DMAC) with thionyl chloride and stoichiometric amounts of reactant amines has been developed. The combined reagent TiCl(4)/NaBH(4) was found to be effective for the reduction of the amide derivatives of TMCA to the corresponding amines.