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论文类型：期刊论文

发表时间：2012-09-01

发表刊物：CHINESE JOURNAL OF CHEMISTRY

收录刊物：SCIE、Scopus

卷号：30

期号：9,SI

页面范围：2109-2114

ISSN号：1001-604X

关键字：organocatalysis; green chemistry; cyanosilylation; quaternary ammonium base; solvent-free

摘要：Quaternary ammonium bases, such as aqueous (CH3)4NOH, were found to be an extraordinarily efficient catalyst for cyanosilylation of aldehydes. The addition reaction of trimethylsilyl cyanide (TMSCN) to equivalent aldehydes could proceed smoothly with turnover frequency (TOF) up to 3000000 h-1 and in near 100% yield under solvent-free conditions. These organic catalysts also tolerated various aldehydes including aromatic, aliphatic and a,beta-unsaturated aldehydes. This process perfectly conforms to the features of green chemistry: no waste regarding side-products and unconverted reactants, solvent-free, excellent catalytic activity, and no requirement for separation.