Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-10-01

Journal: CHINESE JOURNAL OF CHEMISTRY

Included Journals: Scopus、SCIE

Volume: 31

Issue: 10

Page Number: 1269-1273

ISSN: 1001-604X

Key Words: cross-coupling; desulfination; aryl bromides; aryl chlorides; palladium

Abstract: An alternative method for synthesis of biaryls has been developed through the Pd catalyzed desulfitative coupling reaction of sodium arylsulfinates with aryl bromides and chlorides. The procedure tolerates a variety of functional groups, such as cyano, formyl, acetyl, chloro, methoxy, trifluoromethyl and heteroaromatic unit. The desired products were obtained in moderate to excellent yields under relatively mild reaction conditions without additives, base or co-catalyst.