Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-05-14

Journal: ORGANIC & BIOMOLECULAR CHEMISTRY

Included Journals: Scopus、PubMed、EI、SCIE

Volume: 10

Issue: 18

Page Number: 3715-3720

ISSN: 1477-0520

Abstract: In this article, a facile, efficient and practical method for Ni-catalyzed direct C-H amination of benzoxazole with secondary amines has been developed. This procedure requires Ni(OAc)(2)center dot 4H(2)O as catalyst, TBHP as oxidant and acid as the additive. Avariety of substituted benzoxazol-2-amines were synthesized in moderate to good yields.