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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本横滨国立大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 有机化学
办公地点：大连市高新区凌工路2号大连理工大学西部新区F-412
联系方式：大连市高新区凌工路2号大连理工大学西部新区F-412 邮政编码 116024 电话：0411-84986295 电子信箱：ymli@dlut.edu.cn
电子邮箱：ymli@dlut.edu.cn
Efficient Copper-Catalyzed S-Arylation of Thiols with Aryl Bromides and Chlorides
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论文类型：期刊论文
发表时间：2010-11-01
发表刊物：SYNTHESIS-STUTTGART
收录刊物：SCIE、EI、Scopus
期号：21
页面范围：3602-3608
ISSN号：0039-7881
关键字：copper catalyst; aryl bromides; aryl chlorides; cross-coupling; organic sulfides
摘要：An efficient copper-catalyzed system for C-S cross-coupling of aromatic thiols with aryl bromides and chlorides has been developed using 1,2,3,4-tetrahydroquinoline-8-ol as a ligand. It is noteworthy that this method is proved to be especially effective for aryl bromides with electron-donating groups. By this protocol, a variety of thioethers as well as symmetrical and unsymmetrical bis-thioethers are obtained in excellent yields with an exceptional level of functional group tolerance and high chemoselectivity.