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Indexed by:期刊论文

Date of Publication:2017-07-21

Journal:ORGANIC & BIOMOLECULAR CHEMISTRY

Included Journals:SCIE、EI、PubMed

Volume:15

Issue:27

Page Number:5693-5700

ISSN No.:1477-0520

Abstract:A Pd-catalyzed hydrogenation of (Z)-trifluoromethyl alkenyl triflate providing either (Z) -or (E)-3,3,3-trifluoropropenyl derivatives with excellent divergent geometric control in good yield is described. Catalyzed by Pd(OAc)(2)/PPh3, the reduction of (Z)-trifluoromethyl alkenyl triflates with HSiEt3 gave (E)-3,3,3-trifluoropropenyl derivatives, and while using HCOOH/Et3N as the reducing agent, the (Z)-isomers were obtained through an elimination/hydrogenation tandem pathway. Both transformations showed excellent geometrical selectivity.