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Indexed by:期刊论文

Date of Publication:2018-10-01

Journal:JOURNAL OF FLUORINE CHEMISTRY

Included Journals:SCIE

Volume:214

Page Number:42-47

ISSN No.:0022-1139

Key Words:Trifluoromethylation; Coumarins; Photo-catalyzed; Transition-metal-free; Acetone; Langlois reagent

Abstract:A simple, metal- and oxidant-free photo catalysis strategy for the direct trifluoromethylation of coumarins with inexpensive sodium triflinate (Langlois reagent, CF3SO2Na) as the CF3 source under xenon lamp irradiation is described. The reaction proceeds under ambient conditions and affords the corresponding products in moderate yields. The acetone can be used as low-cost radical initiator to generate CF3 radicals from sodium triflinate efficiently.