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论文类型：期刊论文

第一作者：Zhao, Yilong

通讯作者：Zhou, YH (reprint author), Dalian Univ Technol, Sch Pharmaceut Sci & Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China.

合写作者：Zhou, Yuhan,Zhang, Chunxia,Wang, Huan,Zhao, Jinfeng,Jin, Kun,Liu, Jihong,Liu, Jianhui,Qu, Jingping

发表时间：2017-07-21

发表刊物：ORGANIC & BIOMOLECULAR CHEMISTRY

收录刊物：SCIE、EI、PubMed

卷号：15

期号：27

页面范围：5693-5700

ISSN号：1477-0520

摘要：A Pd-catalyzed hydrogenation of (Z)-trifluoromethyl alkenyl triflate providing either (Z) -or (E)-3,3,3-trifluoropropenyl derivatives with excellent divergent geometric control in good yield is described. Catalyzed by Pd(OAc)(2)/PPh3, the reduction of (Z)-trifluoromethyl alkenyl triflates with HSiEt3 gave (E)-3,3,3-trifluoropropenyl derivatives, and while using HCOOH/Et3N as the reducing agent, the (Z)-isomers were obtained through an elimination/hydrogenation tandem pathway. Both transformations showed excellent geometrical selectivity.