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发布时间：2019-03-12

论文类型：期刊论文

发表时间：2017-07-21

发表刊物：ORGANIC & BIOMOLECULAR CHEMISTRY

收录刊物：PubMed、EI、SCIE

卷号：15

期号：27

页面范围：5693-5700

ISSN号：1477-0520

摘要：A Pd-catalyzed hydrogenation of (Z)-trifluoromethyl alkenyl triflate providing either (Z) -or (E)-3,3,3-trifluoropropenyl derivatives with excellent divergent geometric control in good yield is described. Catalyzed by Pd(OAc)(2)/PPh3, the reduction of (Z)-trifluoromethyl alkenyl triflates with HSiEt3 gave (E)-3,3,3-trifluoropropenyl derivatives, and while using HCOOH/Et3N as the reducing agent, the (Z)-isomers were obtained through an elimination/hydrogenation tandem pathway. Both transformations showed excellent geometrical selectivity.