Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2014-02-01

Journal: PLANT CELL REPORTS

Included Journals: Scopus、PubMed、SCIE

Volume: 33

Issue: 2

Page Number: 203-214

ISSN: 0721-7714

Key Words: CBL-CIPK; Ca2+; Abiotic stress; Signaling pathway; ABA; Potassium

Abstract: The calcineurin B-like protein-CBL-interacting protein kinase (CBL-CIPK) signaling pathway in plants is a Ca2+-related pathway that responds strongly to both abiotic and biotic environmental stimuli. The CBL-CIPK system shows variety, specificity, and complexity in response to different stresses, and the CBL-CIPK signaling pathway is regulated by complex mechanisms in plant cells. As a plant-specific Ca2+ sensor relaying pathway, the CBL-CIPK pathway has some crosstalk with other signaling pathways. In addition, research has shown that there is crosstalk between the CBL-CIPK pathway and the low-K+ response pathway, the ABA signaling pathway, the nitrate sensing and signaling pathway, and others. In this paper, we summarize and review research discoveries on the CBL-CIPK network. We focus on the different modification and regulation mechanisms (phosphorylation and dephosphorylation, dual lipid modification) of the CBL-CIPK network, the expression patterns and functions of CBL-CIPK network genes, the responses of this network to abiotic stresses, and its crosstalk with other signaling pathways. We also discuss the technical research methods used to analyze the CBL-CIPK network and some of its newly discovered functions in plants.