Hits:

Date of Publication:2009-01-01

Journal:大连理工大学学报

Affiliation of Author(s):化工学院

Issue:4

Page Number:482-487

ISSN No.:1000-8608

Abstract:To study the chemical constituents of aerial part of Gentiana scabra Bunge,the plant material was extracted with ethanol,and the constituents were separated and purified from the ethanol extraction by silica gel column chromatography.Their structures were identified as 6-demethoxy-7-methylcapillarisin (Ⅵ) and five other compounds,β-Amyrin(I),β-Sitosterol (II),β-Amyrin acetate (Ⅲ),Uvaol (IV) and Oleanolic acid (V) on the basis of physicochemical properties and spectral methods.Among them,Compound Ⅵ was isolated from Gentianaceae family for the first time.Its characterization of 1D and 2D NMR spectra and possible fragmentation pathway in EI-MS were discussed.The crystal structure of Compound Ⅵ was determined to be orthorhombic and Pbca space group by X-ray crystallographic analysis.Crystal data are as follows:a=1.291 83(19)nm, b=0.721 19(15)nm,c=2.923 7(5)nm,α=90°,β=90°,γ=90°,V=2.723 9(8)nm~3,Z=8,D_c=1.464 g/m~3,μ=0.114 mm~(-1),F(000)=1 248.The dihedral angle between B ring and A/C ring is 99.6°.There are π-π stacking interactions between molecules.

Note:新增回溯数据