Release Time:2021-09-03  Hits:

Indexed by: Journal Papers

Date of Publication: 2020-12-29

Journal: GREEN CHEMISTRY

Volume: 22

Issue: 8

Page Number: 2394-2398

ISSN: 1463-9262

Abstract: An orthogonal and regioselective synthesis of triazole disulfides in aqueous media under mild conditions has been developed. This simple and practical approach is environment-friendly and compatible with oxygen/water and various complex biological media. It features excellent regioselectivities and chemoselectivities, high yields, good biocompatibility and bioorthogonality. Its applications in the synthesis of carbohydrates and trigger-responsive nanoparticles are further highlights of this aqueous transformation.