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论文类型：期刊论文

发表时间：2016-07-07

发表刊物：TETRAHEDRON

收录刊物：SCIE、Scopus

卷号：72

期号：27-28

页面范围：3858-3862

ISSN号：0040-4020

关键字：Trifluoromethylation; Decarboxylative coupling reaction; Arylpropiolic acids; Trifluoromethylated acetylenes; Cu(I)/Ag(I)-mediated

摘要：A novel Cu(I)/Ag(I)-mediated decarboxylative trifluoromethylation of arylpropiolic acids with Me3SiCF3 has been developed for the construction of Csp-CF3 bond under mild conditions. This method proceeds smoothly at room temperature and shows a widely functional compatibility, providing a series of corresponding trifluoromethylated acetylenyl-containing aromatics in good yields. (C) 2016 Elsevier Ltd. All rights reserved.