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Indexed by:期刊论文

Date of Publication:2014-09-15

Journal:TETRAHEDRON-ASYMMETRY

Included Journals:SCIE、Scopus

Volume:25

Issue:16-17

Page Number:1215-1220

ISSN No.:0957-4166

Abstract:Easily accessible diterpenoid alkaloid derivatives have been used as organocatalysts in the enantioselective alpha-chlorination of beta-oxo esters. The treatment of beta-oxo esters with N-chlorophthalimide (NCP) as a chlorine source under mild reaction conditions afforded the corresponding alpha-chlorinated beta-oxo esters in excellent yields (up to 98%) and with moderate enantioselectivities (up to 68% ee) in 30 mm. (C) 2014 Elsevier Ltd. All rights reserved.