Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2014-09-15

Journal: TETRAHEDRON-ASYMMETRY

Included Journals: Scopus、SCIE

Volume: 25

Issue: 16-17

Page Number: 1215-1220

ISSN: 0957-4166

Abstract: Easily accessible diterpenoid alkaloid derivatives have been used as organocatalysts in the enantioselective alpha-chlorination of beta-oxo esters. The treatment of beta-oxo esters with N-chlorophthalimide (NCP) as a chlorine source under mild reaction conditions afforded the corresponding alpha-chlorinated beta-oxo esters in excellent yields (up to 98%) and with moderate enantioselectivities (up to 68% ee) in 30 mm. (C) 2014 Elsevier Ltd. All rights reserved.