Hits:

Indexed by:期刊论文

Date of Publication:2014-12-07

Journal:NANOSCALE

Included Journals:SCIE、EI

Volume:6

Issue:23

Page Number:14388-14393

ISSN No.:2040-3364

Abstract:A new near-infrared light-controlled drug delivery system based on caged gold nanorods (CGNRs) is demonstrated. The loading and release process of drug payloads into/from CGNR nanocarriers were systematically investigated. The drug-loaded CGNR constructs could enable combined chemotherapy and photo-thermal effects in killing tumor cells upon light irradiation, therefore, enhance the killing efficiency. In conjunction with visibility under quenching-free dark-field imaging, CGNRs may serve as multifunctional theranostic reagents towards cancer diagnostics and therapeutics.