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Indexed by:期刊论文

Date of Publication:2015-02-26

Journal:RSC ADVANCES

Included Journals:SCIE、EI、Scopus

Volume:5

Issue:30

Page Number:23646-23649

ISSN No.:2046-2069

Abstract:We have developed a terminal alkyne substituted O6-benzylguanine, named PYBG, as a versatile precursor to be facilely conjugated with various fluorescent dyes through 'Click chemistry' and Sonogashira coupling reactions. These fluorescent PYBG derivatives specifically and efficiently label the target genetically encoded SNAP-tags in live cells.