Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2015-02-26

Journal: RSC ADVANCES

Included Journals: Scopus、EI、SCIE

Volume: 5

Issue: 30

Page Number: 23646-23649

ISSN: 2046-2069

Abstract: We have developed a terminal alkyne substituted O6-benzylguanine, named PYBG, as a versatile precursor to be facilely conjugated with various fluorescent dyes through 'Click chemistry' and Sonogashira coupling reactions. These fluorescent PYBG derivatives specifically and efficiently label the target genetically encoded SNAP-tags in live cells.